Critically Ill Patient with Multidrug-Resistant Acinetobacter baumannii Respiratory Infection Successfully Treated with Intravenous and Nebulized Bacteriophage Therapy

Sohail Rao*, Monica Betancourt-Garcia, Yetunde O. Kare-Opaneye, Brett E. Swierczewski, Jason W. Bennett, Bri'Anna Horne, Joseph Fackler, Lia Patricia Suazo Hernandez, Michael J. Brownstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Hospitalized patients are at risk of developing serious multidrug resistant bacterial infections. This risk is heightened in patients who are on mechanical ventilation, are immunocompromised, and/or have chronic comorbidities. We report the case of a 52-year-old critically ill patient with a multidrug resistant Acinetobacter baumannii (MDR-A) respiratory infection who was successfully treated with antibiotics and intravenous and nebulized bacteriophage therapy.

Original languageEnglish
Article numbere00824-21
JournalAntimicrobial Agents and Chemotherapy
Volume66
Issue number1
DOIs
StatePublished - Jan 2022
Externally publishedYes

Keywords

  • Acinetobacter
  • Acinetobacter baumannii
  • Bacteriophage
  • Bacteriophage therapy
  • Mechanical ventilation
  • Multidrug resistance
  • Multidrug-resistant bacterial infection

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