Retinal vein occlusions are common causes of ocular morbidity. Traditional treatment modalities, guided by the Branch Vein Occlusion Study and Central Vein Occlusion Study, have attempted to reduce ocular complications arising from these conditions and improve visual acuity through targeted laser photocoagulation. In addition, surgical techniques have been used in select cases to improve visual outcomes. More recently, novel pharmacotherapies have become useful modalities in improving visual outcomes for patients with vein occlusions. This review will identify and offer a management strategy to assist in the treatment of vision-threatening complications of retinal vein occlusions.