Cutaneous leukocytoclastic vasculitis associated with levofloxacin therapy

Dana M. Blyth*, Elizabeth Markelz, Jason F. Okulicz

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Many cases of cutaneous vasculitis are druginduced with histology revealing leukocytoclastic vasculitis (LCV). We present a case of levofloxacin-associated LCV successfully treated with prednisone and cessation of the offending drug. Although case reports describe a link between LCV and older fluoroquinolones, such as ciprofloxacin and ofloxacin, recent reports have implicated the newer fluoroquinolone levofloxacin. Recognition of fluoroquinoloneinduced cutaneous vasculitis is important as continuation or re-exposure of the offending agent may have life-threatening consequences.

Original languageEnglish
Pages (from-to)35-37
Number of pages3
JournalInfectious Disease Reports
Issue number1
StatePublished - 2012
Externally publishedYes


  • Drug induced cutaneous vasculitis
  • Fluoroquinolone
  • Leukocytoclastic vasculitis
  • Levofloxacin


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