Desmoid tumors of the chest wall.

P. J. Allen*, C. D. Shriver

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Desmoid tumors are rare soft tissue neoplasms derived from fascial or musculoaponeurotic structures. These tumors are histologically benign but may behave aggressively at the local level with multiple recurrences after complete resection being common. Chest wall desmoids account for approximately 20% of all patients with desmoid tumors. Patients with these lesions are often asymptomatic and thus commonly present with lesions greater than 10 cm in size. The treatment for these neoplasms remains margin negative surgical excision, and, given the often large size at presentation, may require extensive chest wall resection. When this is required, chest wall reconstruction with either prosthetic material and/or autologous tissue may be performed. There may be recurrence in as many as 75% of patients. Neither adjuvant radiotherapy or chemotherapy have been shown to reduce the rate of recurrence. Recurrence should also be treated with surgical resection because patients who undergo complete surgical resection of recurrence are as likely to remain disease free after resection as patients who present with primary disease.

Original languageEnglish
Pages (from-to)264-269
Number of pages6
JournalSeminars in Thoracic and Cardiovascular Surgery
Issue number3
StatePublished - Jul 1999
Externally publishedYes


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