TY - JOUR
T1 - Detection of cefiderocol and aztreonam/avibactam resistance in epidemic
Escherichia coli ST-361 carrying
bla
NDM-5 and
bla
KPC-3 from foreign fighters evacuated from Ukraine.
AU - Martin, Melissa J
AU - Luo, Ting L
AU - Kovalchuk, Valentyn
AU - Kondratiuk, Viacheslav
AU - Dao, Henry D
AU - Kovalenko, Iryna
AU - Plaza, Brandon J
AU - Kettlewell, Joanna M
AU - Anderson, Cole P
AU - Smedberg, Jason R
AU - Ong, Ana C
AU - Kwak, Yoon I
AU - Hawley-Molloy, Joshua S
AU - Bennett, Jason W
AU - McGann, Patrick T
AU - Lebreton, Francois
PY - 2024/9/20
Y1 - 2024/9/20
N2 - Genomic surveillance detected clonal
Escherichia coli sequence type-361 isolates carrying
bla
NDM-5,
bla
KPC-3,
bla
CTX-M-15, and
rmtB1 from a patient in Ukraine and four wounded foreign soldiers evacuated to Germany. Isolates were non-susceptible to carbapenems, aminoglycosides, and cefiderocol and aztreonam/avibactam due to a PBP3 YRIN insertion and the
bla
CMY-145 AmpC β-lactamase. Coordinated surveillance efforts across civilian, military, and veteran healthcare systems are essential to prevent further spread as international volunteers return home after medical evacuation from Ukraine.
AB - Genomic surveillance detected clonal
Escherichia coli sequence type-361 isolates carrying
bla
NDM-5,
bla
KPC-3,
bla
CTX-M-15, and
rmtB1 from a patient in Ukraine and four wounded foreign soldiers evacuated to Germany. Isolates were non-susceptible to carbapenems, aminoglycosides, and cefiderocol and aztreonam/avibactam due to a PBP3 YRIN insertion and the
bla
CMY-145 AmpC β-lactamase. Coordinated surveillance efforts across civilian, military, and veteran healthcare systems are essential to prevent further spread as international volunteers return home after medical evacuation from Ukraine.
U2 - 10.1128/aac.01090-24
DO - 10.1128/aac.01090-24
M3 - Article
C2 - 39302119
SN - 0066-4804
SP - e0109024
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
ER -