Detection of diverse HIV-1 genetic subtypes in the USA

S. K. Brodine*, F. C. Garland, J. R. Mascola, K. R. Porter, J. R. Mascola, A. W. Artenstein, D. S. Burke, P. J. Weiss, F. E. McCutchan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

118 Scopus citations


Of the nine genetic subtypes of HIV-1 that exist world wide, subtype B predominates in North America and Europe. Thus, most knowledge about HIV-1 and most vaccine development efforts are based on subtype B viruses. We document here the detection of HIV-1 subtypes A, D, and E in five US servicemen who acquired these non-subtype-B infections during overseas deployments. The dispersal of diverse HIV-1 subtypes into regions of the world with previously restricted genetic diversity may have important implications for the epidemiology of the epidemic and for the design and implementation of vaccine trials.

Original languageEnglish
Pages (from-to)1198-1199
Number of pages2
JournalThe Lancet
Issue number8984
StatePublished - 4 Nov 1995
Externally publishedYes


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