Detection of IgA class antibody to hepatitis E virus in serum samples from patients with hepatitis E virus infection

Kurt H. Chau, George J. Dawson, Khalif M. Bile, Lars O. Magnius, Maria H. Sjogren, Isa K. Mushahwar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Scopus citations

Abstract

A newly developed assay for IgA class antibody to hepatitis E virus (IgA anti‐HEV) was used to study 145 serum samples collected during an outbreak of an enterically transmitted hepatitis that occurred in 3 villages in the lower Shebeli region of Southern Somalia between January, 1988 and November, 1989. A total of 52.4% of the afflicted patients were found positive for IgA anti‐HEV, and 73.1% of these were also positive for IgM. Both antibodies disappeared during the convalescence period. Similar results were also seen in serum obtained from sporadic cases of acute waterborne hepatitis in Pakistan. © 1993 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)334-338
Number of pages5
JournalJournal of Medical Virology
Volume40
Issue number4
DOIs
StatePublished - Aug 1993
Externally publishedYes

Keywords

  • HEV infection
  • anti‐HEV antibodies
  • hepatitis E virus HEV

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