TY - JOUR
T1 - Detection of Neisseria gonorrhoeae from Joint Aspirate by Metagenomic Sequencing in Disseminated Gonococcal Infection
AU - Asmerom, Betial
AU - Drobish, Ian
AU - Winckler, Britanny
AU - Chiang, Leslie
AU - Farnaes, Lauge
AU - Beauchamp-Walters, Julia
AU - Bradley, John S.
AU - Ramchandar, Nanda
N1 - Publisher Copyright:
© 2020 The Author(s) 2020. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].
PY - 2021/3/1
Y1 - 2021/3/1
N2 - Disseminated gonococcal infection (DGI) often manifests as gonococcal arthritis and may carry significant morbidity. However, diagnosis remains elusive due to limited sensitivity of available diagnostic tests. We used metagenomic next-generation sequencing to detect Neisseria gonorrhoeae from culture-negative joint aspirates of 2 patients with clinically diagnosed DGI.
AB - Disseminated gonococcal infection (DGI) often manifests as gonococcal arthritis and may carry significant morbidity. However, diagnosis remains elusive due to limited sensitivity of available diagnostic tests. We used metagenomic next-generation sequencing to detect Neisseria gonorrhoeae from culture-negative joint aspirates of 2 patients with clinically diagnosed DGI.
KW - disseminated gonococcal infection
KW - metagenomics
KW - next-generation sequencing
UR - http://www.scopus.com/inward/record.url?scp=85104047017&partnerID=8YFLogxK
U2 - 10.1093/jpids/piaa108
DO - 10.1093/jpids/piaa108
M3 - Article
C2 - 32964934
AN - SCOPUS:85104047017
SN - 2048-7193
VL - 10
SP - 367
EP - 369
JO - Journal of the Pediatric Infectious Diseases Society
JF - Journal of the Pediatric Infectious Diseases Society
IS - 3
ER -