Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary

Joseph T. McCabe; Elke Lehmann; Nicole Chastrette; Jorg Hänze; Rudolf E. Lang; Detlev Ganten; Donald W. Pfaff

doi:10.1016/0169-328X(90)90046-G

Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary

Joseph T. McCabe^*
, Elke Lehmann
, Nicole Chastrette
, Jorg Hänze
, Rudolf E. Lang
, Detlev Ganten
, Donald W. Pfaff

^*Corresponding author for this work

Anatomy, Physiology, and Genetics

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

A messenger ribonucleic acid (mRNA) homologous to the transcript that encodes vasopressin (VP) was detected in the neurointermediate lobe (NIL) of the rat pituitary. The abundance of this transcript is approximately 1/100th the amount detected in the hypothalamus. In rats drinking 2% naCl-water for 0, 2, 4, or 10 days, or for 10 days and then tap water for 14 days, the levels of VP mRNA in the NIL were altered in a fashion that paralleled changes in the hypothalamus.

Original language	English
Pages (from-to)	325-329
Number of pages	5
Journal	Molecular Brain Research
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/0169-328X(90)90046-G
State	Published - Oct 1990

Keywords

Antidiuretic hormone
Gene expression
Hypothalamus
mRNA
Neurointermediate lobe
Nucleic acid hybridization
Posterior pituitary
Vasopressin

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10.1016/0169-328X(90)90046-G

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title = "Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary",

abstract = "A messenger ribonucleic acid (mRNA) homologous to the transcript that encodes vasopressin (VP) was detected in the neurointermediate lobe (NIL) of the rat pituitary. The abundance of this transcript is approximately 1/100th the amount detected in the hypothalamus. In rats drinking 2\% naCl-water for 0, 2, 4, or 10 days, or for 10 days and then tap water for 14 days, the levels of VP mRNA in the NIL were altered in a fashion that paralleled changes in the hypothalamus.",

keywords = "Antidiuretic hormone, Gene expression, Hypothalamus, mRNA, Neurointermediate lobe, Nucleic acid hybridization, Posterior pituitary, Vasopressin",

author = "McCabe, \{Joseph T.\} and Elke Lehmann and Nicole Chastrette and Jorg H{\"a}nze and Lang, \{Rudolf E.\} and Detlev Ganten and Pfaff, \{Donald W.\}",

year = "1990",

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language = "English",

volume = "8",

pages = "325--329",

journal = "Molecular Brain Research",

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T1 - Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary

AU - McCabe, Joseph T.

AU - Lehmann, Elke

AU - Chastrette, Nicole

AU - Hänze, Jorg

AU - Lang, Rudolf E.

AU - Ganten, Detlev

AU - Pfaff, Donald W.

PY - 1990/10

Y1 - 1990/10

N2 - A messenger ribonucleic acid (mRNA) homologous to the transcript that encodes vasopressin (VP) was detected in the neurointermediate lobe (NIL) of the rat pituitary. The abundance of this transcript is approximately 1/100th the amount detected in the hypothalamus. In rats drinking 2% naCl-water for 0, 2, 4, or 10 days, or for 10 days and then tap water for 14 days, the levels of VP mRNA in the NIL were altered in a fashion that paralleled changes in the hypothalamus.

AB - A messenger ribonucleic acid (mRNA) homologous to the transcript that encodes vasopressin (VP) was detected in the neurointermediate lobe (NIL) of the rat pituitary. The abundance of this transcript is approximately 1/100th the amount detected in the hypothalamus. In rats drinking 2% naCl-water for 0, 2, 4, or 10 days, or for 10 days and then tap water for 14 days, the levels of VP mRNA in the NIL were altered in a fashion that paralleled changes in the hypothalamus.

KW - Antidiuretic hormone

KW - Gene expression

KW - Hypothalamus

KW - mRNA

KW - Neurointermediate lobe

KW - Nucleic acid hybridization

KW - Posterior pituitary

KW - Vasopressin

UR - https://www.scopus.com/pages/publications/0024992381

U2 - 10.1016/0169-328X(90)90046-G

DO - 10.1016/0169-328X(90)90046-G

M3 - Article

C2 - 2176710

AN - SCOPUS:0024992381

SN - 0169-328X

VL - 8

SP - 325

EP - 329

JO - Molecular Brain Research

JF - Molecular Brain Research

IS - 4

ER -

Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary

Abstract

Keywords

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