Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma

X. P. Chen; Y. J. Dong; W. P. Guo; W. Wang; M. H. Li; J. Xu; J. S. Dumler; Y. Z. Zhang

doi:10.1016/j.cmi.2014.09.008

Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma

X. P. Chen, Y. J. Dong, W. P. Guo, W. Wang, M. H. Li, J. Xu, J. S. Dumler, Y. Z. Zhang^*

^*Corresponding author for this work

Pathology

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Wolbachia 16S rRNA and fbpA genes were twice detected over 5 days in the blood of a patient with high fever. The patient was given fluoroquinolones and the fever resolved. Four weeks later, he was diagnosed with non-Hodgkin's lymphoma and received R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) treatment resulting in complete remission. This is the first report of detection of Wolbachia genes from the blood of human patients with non-Hodgkin's lymphoma.

Original language	English
Pages (from-to)	182.e1-182.e4
Journal	Clinical Microbiology and Infection
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/j.cmi.2014.09.008
State	Published - 1 Feb 2015

Keywords

Infection
Non-Hodgkin lymphoma
Wolbachia agent

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10.1016/j.cmi.2014.09.008

Cite this

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title = "Detection of Wolbachia genes in a patient with non-Hodgkin's lymphoma",

abstract = "Wolbachia 16S rRNA and fbpA genes were twice detected over 5 days in the blood of a patient with high fever. The patient was given fluoroquinolones and the fever resolved. Four weeks later, he was diagnosed with non-Hodgkin's lymphoma and received R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) treatment resulting in complete remission. This is the first report of detection of Wolbachia genes from the blood of human patients with non-Hodgkin's lymphoma.",

keywords = "Infection, Non-Hodgkin lymphoma, Wolbachia agent",

author = "Chen, {X. P.} and Dong, {Y. J.} and Guo, {W. P.} and W. Wang and Li, {M. H.} and J. Xu and Dumler, {J. S.} and Zhang, {Y. Z.}",

note = "Publisher Copyright: {\textcopyright} 2014 European Society of Clinical Microbiology and Infectious Diseases.",

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AU - Dong, Y. J.

AU - Guo, W. P.

AU - Wang, W.

AU - Li, M. H.

AU - Xu, J.

AU - Dumler, J. S.

AU - Zhang, Y. Z.

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AB - Wolbachia 16S rRNA and fbpA genes were twice detected over 5 days in the blood of a patient with high fever. The patient was given fluoroquinolones and the fever resolved. Four weeks later, he was diagnosed with non-Hodgkin's lymphoma and received R-CHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone) treatment resulting in complete remission. This is the first report of detection of Wolbachia genes from the blood of human patients with non-Hodgkin's lymphoma.

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