Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

James C. Dunford; Aneika Falconer; Laura N. Leite; Robert A. Wirtz; William G. Brogdon

doi:10.1093/jme/tjv239

Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

James C. Dunford, Aneika Falconer, Laura N. Leite, Robert A. Wirtz, William G. Brogdon

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC50 and LC90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC50 of 160.3 µg a.i/bottle (147.6-182.7) and LC90 of 282.8 (233.2-394.2) in Ae. aegypti; five concentrations yielded an LC50 of 125.4 (116.1-137.6) and LC90 of 192.5 (165.0-278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.

Original language	English
Pages (from-to)	699-702
Number of pages	4
Journal	Journal of Medical Entomology
Volume	53
Issue number	3
DOIs	https://doi.org/10.1093/jme/tjv239
State	Published - 1 May 2016
Externally published	Yes

Keywords

Aedes
C8910
LC50
LC90
bioassay

Access to Document

10.1093/jme/tjv239

Cite this

@article{1e54b6fd9e6f4f4fb8cb55937f39333f,

title = "Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)",

abstract = "Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC50 and LC90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC50 of 160.3 µg a.i/bottle (147.6-182.7) and LC90 of 282.8 (233.2-394.2) in Ae. aegypti; five concentrations yielded an LC50 of 125.4 (116.1-137.6) and LC90 of 192.5 (165.0-278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.",

keywords = "Aedes, C8910, LC50, LC90, bioassay",

author = "Dunford, {James C.} and Aneika Falconer and Leite, {Laura N.} and Wirtz, {Robert A.} and Brogdon, {William G.}",

note = "Publisher Copyright: Published by Oxford University Press on behalf of Entomological Society of America 2015. This work is written by US Government employees and is in the public domain in the US.",

year = "2016",

month = may,

day = "1",

doi = "10.1093/jme/tjv239",

language = "English",

volume = "53",

pages = "699--702",

journal = "Journal of Medical Entomology",

issn = "0022-2585",

number = "3",

}

Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae). / Dunford, James C.; Falconer, Aneika; Leite, Laura N. et al.
In: Journal of Medical Entomology, Vol. 53, No. 3, 01.05.2016, p. 699-702.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

AU - Dunford, James C.

AU - Falconer, Aneika

AU - Leite, Laura N.

AU - Wirtz, Robert A.

AU - Brogdon, William G.

N1 - Publisher Copyright: Published by Oxford University Press on behalf of Entomological Society of America 2015. This work is written by US Government employees and is in the public domain in the US.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC50 and LC90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC50 of 160.3 µg a.i/bottle (147.6-182.7) and LC90 of 282.8 (233.2-394.2) in Ae. aegypti; five concentrations yielded an LC50 of 125.4 (116.1-137.6) and LC90 of 192.5 (165.0-278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.

AB - Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC50 and LC90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC50 of 160.3 µg a.i/bottle (147.6-182.7) and LC90 of 282.8 (233.2-394.2) in Ae. aegypti; five concentrations yielded an LC50 of 125.4 (116.1-137.6) and LC90 of 192.5 (165.0-278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.

KW - Aedes

KW - C8910

KW - LC50

KW - LC90

KW - bioassay

UR - http://www.scopus.com/inward/record.url?scp=85017113505&partnerID=8YFLogxK

U2 - 10.1093/jme/tjv239

DO - 10.1093/jme/tjv239

M3 - Article

C2 - 26718717

AN - SCOPUS:85017113505

SN - 0022-2585

VL - 53

SP - 699

EP - 702

JO - Journal of Medical Entomology

JF - Journal of Medical Entomology

IS - 3

ER -

Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

Abstract

Keywords

Access to Document

Fingerprint

Cite this