TY - JOUR
T1 - Determination of susceptibilities of 26 Leptospira sp. serovars to 24 antimicrobial agents by a broth microdilution technique
AU - Murray, Clinton K.
AU - Hospenthal, Duane R.
PY - 2004/10
Y1 - 2004/10
N2 - The MICs of 24 antimicrobials for 26 Leptospira spp. serovars were determined using a broth microdilution technique. The MICs at which 90% of isolates tested were inhibited (MIC90s) of cefepime, imipenem-cilastatin, erythromycin, clarithromycin, and telithromycin were all ≤0.01 μg/ml. The MIC90s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were ≥3.13 μg/ml. Many antimicrobials have excellent in vitro activity against Leptospira.
AB - The MICs of 24 antimicrobials for 26 Leptospira spp. serovars were determined using a broth microdilution technique. The MICs at which 90% of isolates tested were inhibited (MIC90s) of cefepime, imipenem-cilastatin, erythromycin, clarithromycin, and telithromycin were all ≤0.01 μg/ml. The MIC90s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were ≥3.13 μg/ml. Many antimicrobials have excellent in vitro activity against Leptospira.
UR - http://www.scopus.com/inward/record.url?scp=4644337295&partnerID=8YFLogxK
U2 - 10.1128/AAC.48.10.4002-4005.2004
DO - 10.1128/AAC.48.10.4002-4005.2004
M3 - Article
C2 - 15388465
AN - SCOPUS:4644337295
SN - 0066-4804
VL - 48
SP - 4002
EP - 4005
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 10
ER -