Diagnostic proteomics: Serum proteomic patterns for the detection of early stage cancers

Li Rong Yu, Ming Zhou, Thomas P. Conrads, Timothy D. Veenstra*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The ability to interrogate thousands of proteins found in complex biological samples using proteomic technologies has brought the hope of discovering novel disease-specific biomarkers. While most proteomic technologies used to discover diagnostic biomarkers are quite sophisticated, "proteomic pattern analysis" has emerged as a simple, yet potentially revolutionary, method for the early diagnosis of diseases. Utilizing this technology, hundreds of clinical samples can be analyzed per day and several preliminary studies suggest proteomic pattern analysis has the potential to be a novel, highly sensitive diagnostic tool for the early detection of cancer.

Original languageEnglish
Pages (from-to)209-218
Number of pages10
JournalDisease Markers
Volume19
Issue number4-5
DOIs
StatePublished - 2003
Externally publishedYes

Keywords

  • Cancer detection
  • Mass spectrometry
  • Proteomic patterns
  • Serum

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