Disasters Resulting from Radiologic and Nuclear Events

John S. Parrish; Gilbert Seda

doi:10.1016/j.ccc.2019.06.005

Disasters Resulting from Radiologic and Nuclear Events

John S. Parrish^*, Gilbert Seda

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.

Original language	English
Pages (from-to)	619-631
Number of pages	13
Journal	Critical Care Clinics
Volume	35
Issue number	4
DOIs	https://doi.org/10.1016/j.ccc.2019.06.005
State	Published - Oct 2019
Externally published	Yes

Keywords

Acute radiation syndrome
Biodosimetry
Chelating agents
Colony-stimulating factors
Internal contamination
Radiation injury

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10.1016/j.ccc.2019.06.005

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title = "Disasters Resulting from Radiologic and Nuclear Events",

abstract = "Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.",

keywords = "Acute radiation syndrome, Biodosimetry, Chelating agents, Colony-stimulating factors, Internal contamination, Radiation injury",

author = "Parrish, {John S.} and Gilbert Seda",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = oct,

doi = "10.1016/j.ccc.2019.06.005",

language = "English",

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pages = "619--631",

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AU - Parrish, John S.

AU - Seda, Gilbert

PY - 2019/10

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N2 - Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.

AB - Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.

KW - Acute radiation syndrome

KW - Biodosimetry

KW - Chelating agents

KW - Colony-stimulating factors

KW - Internal contamination

KW - Radiation injury

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M3 - Review article

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AN - SCOPUS:85071033937

SN - 0749-0704

VL - 35

SP - 619

EP - 631

JO - Critical Care Clinics

JF - Critical Care Clinics

IS - 4

ER -

Disasters Resulting from Radiologic and Nuclear Events

Abstract

Keywords

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