TY - JOUR
T1 - Disasters Resulting from Radiologic and Nuclear Events
AU - Parrish, John S.
AU - Seda, Gilbert
N1 - Publisher Copyright:
© 2019
PY - 2019/10
Y1 - 2019/10
N2 - Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.
AB - Radiation accidents are rare, but can produce large numbers of casualties with predictable patterns of injury. Casualties may suffer from a wide range of radiation exposures. Triage based on presence or absence of conventional injuries and an accurate assessment of radiation dose based on event history, symptoms, and laboratory testing, is critical. Treatment of acute radiation syndrome is supportive: including fluids, antibiotics, blood products, colony-stimulating factors, and stem cell or bone marrow transplantation. Care of radiation-injured patients with conventional trauma or burns needs to be modified to account for adverse effects of radiation on wound healing and susceptibility to infections.
KW - Acute radiation syndrome
KW - Biodosimetry
KW - Chelating agents
KW - Colony-stimulating factors
KW - Internal contamination
KW - Radiation injury
UR - http://www.scopus.com/inward/record.url?scp=85071033937&partnerID=8YFLogxK
U2 - 10.1016/j.ccc.2019.06.005
DO - 10.1016/j.ccc.2019.06.005
M3 - Review article
C2 - 31445609
AN - SCOPUS:85071033937
SN - 0749-0704
VL - 35
SP - 619
EP - 631
JO - Critical Care Clinics
JF - Critical Care Clinics
IS - 4
ER -