Donor organ preservation effects on the recipient

The objective of preservation studies is to extend storage times and to minimize ischemic and reperfusion injury in the harvested organ. Clinical studies compare different perfusates and preservation techniques for liver, kidney, pancreas, small bowel, heart, and lung allografts. Although advances in preservation solutions and methods continue to result in outcome improvements for the recipient, the impact of prolonged cold ischemia times and the importance of minimizing its negative effects should not be overlooked.