Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya

Abigael Mbaisi; Pamela Liyala; Fredrick Eyase; Rachel Achilla; Hosea Akala; Julia Wangui; Josphat Mwangi; Finnley Osuna; Uzma Alam; Bonnie L. Smoak; Jon M. Davis; Dennis E. Kyle; Rodney L. Coldren; Carl Mason; Norman C. Waters

doi:10.1128/AAC.48.9.3598-3601.2004

Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya

Abigael Mbaisi, Pamela Liyala, Fredrick Eyase, Rachel Achilla, Hosea Akala, Julia Wangui, Josphat Mwangi, Finnley Osuna, Uzma Alam, Bonnie L. Smoak, Jon M. Davis, Dennis E. Kyle, Rodney L. Coldren, Carl Mason, Norman C. Waters^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.

Original language	English
Pages (from-to)	3598-3601
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	48
Issue number	9
DOIs	https://doi.org/10.1128/AAC.48.9.3598-3601.2004
State	Published - Sep 2004
Externally published	Yes

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Mbaisi, A., Liyala, P., Eyase, F., Achilla, R., Akala, H., Wangui, J., Mwangi, J., Osuna, F., Alam, U., Smoak, B. L., Davis, J. M., Kyle, D. E., Coldren, R. L., Mason, C., & Waters, N. C. (2004). Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya. Antimicrobial Agents and Chemotherapy, 48(9), 3598-3601. https://doi.org/10.1128/AAC.48.9.3598-3601.2004

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abstract = "The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.",

author = "Abigael Mbaisi and Pamela Liyala and Fredrick Eyase and Rachel Achilla and Hosea Akala and Julia Wangui and Josphat Mwangi and Finnley Osuna and Uzma Alam and Smoak, {Bonnie L.} and Davis, {Jon M.} and Kyle, {Dennis E.} and Coldren, {Rodney L.} and Carl Mason and Waters, {Norman C.}",

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Mbaisi, A, Liyala, P, Eyase, F, Achilla, R, Akala, H, Wangui, J, Mwangi, J, Osuna, F, Alam, U, Smoak, BL, Davis, JM, Kyle, DE, Coldren, RL, Mason, C & Waters, NC 2004, 'Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya', Antimicrobial Agents and Chemotherapy, vol. 48, no. 9, pp. 3598-3601. https://doi.org/10.1128/AAC.48.9.3598-3601.2004

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T1 - Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya

AU - Mbaisi, Abigael

AU - Liyala, Pamela

AU - Eyase, Fredrick

AU - Achilla, Rachel

AU - Akala, Hosea

AU - Wangui, Julia

AU - Mwangi, Josphat

AU - Osuna, Finnley

AU - Alam, Uzma

AU - Smoak, Bonnie L.

AU - Davis, Jon M.

AU - Kyle, Dennis E.

AU - Coldren, Rodney L.

AU - Mason, Carl

AU - Waters, Norman C.

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AB - The drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profiles. We observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.

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Drug susceptibility and genetic evaluation of Plasmodium falciparum isolates obtained in four distinct geographical regions of Kenya

Abstract

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