Effects of nicotine on body weight, food consumption and body composition in male rats

Suzan E. Winders*, Neil E. Grunberg

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

67 Scopus citations

Abstract

The present study examined the effects of nicotine administration and cessation on body weight, food consumption, and body composition in rats. Administration of nicotine was associated with attenuated body weight gains and cessation was associated with accelerated body weight gains. Changes in fat composition paralleled changes in body weight, whereas changes in body water and protein did not. These results suggest that nicotine administration decreases body weight through its effects on fat stores in the body. After cessation of nicotine, body fat rapidly approached levels of control animals.

Original languageEnglish
Pages (from-to)1523-1530
Number of pages8
JournalLife Sciences
Volume46
Issue number21
DOIs
StatePublished - 1990
Externally publishedYes

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