TY - JOUR
T1 - Effects of Obstructive Sleep Apnea and CPAP on Cognitive Function
AU - Seda, Gilbert
AU - Matwiyoff, Gregory
AU - Parrish, John S.
N1 - Publisher Copyright:
© 2021, This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.
PY - 2021/7
Y1 - 2021/7
N2 - Purpose of Review: Obstructive sleep apnea (OSA) is characterized by repetitive episodes of complete or partial upper airway obstruction during sleep. Studies indicate that OSA is an independent risk factor for cognitive decline in older patients. The purpose of this paper is to critically review the recent literature on the cognitive effects of untreated OSA and the benefits of treatment across cognitive domains. Recent Findings: OSA’s greatest impact appears to be on attention, vigilance, and information processing speed. Furthermore, the presence of OSA seems to have a significant impact on development and progression of mild cognitive impairment (MCI). Impact of OSA treatment, particularly with CPAP, appears to mitigate and slow the rate of cognitive decline and may reduce the risk of dementia. Summary: Larger properly controlled studies, of a prospective nature, are required to further elucidate the degree of treatment effect. More studies are needed on other treatments for OSA such as oral mandibular devices and hypoglossal nerve stimulation.
AB - Purpose of Review: Obstructive sleep apnea (OSA) is characterized by repetitive episodes of complete or partial upper airway obstruction during sleep. Studies indicate that OSA is an independent risk factor for cognitive decline in older patients. The purpose of this paper is to critically review the recent literature on the cognitive effects of untreated OSA and the benefits of treatment across cognitive domains. Recent Findings: OSA’s greatest impact appears to be on attention, vigilance, and information processing speed. Furthermore, the presence of OSA seems to have a significant impact on development and progression of mild cognitive impairment (MCI). Impact of OSA treatment, particularly with CPAP, appears to mitigate and slow the rate of cognitive decline and may reduce the risk of dementia. Summary: Larger properly controlled studies, of a prospective nature, are required to further elucidate the degree of treatment effect. More studies are needed on other treatments for OSA such as oral mandibular devices and hypoglossal nerve stimulation.
KW - Attention
KW - Cognition
KW - Continuous positive airway pressure (CPAP)
KW - Executive function
KW - Memory
KW - Obstructive sleep apnea
UR - http://www.scopus.com/inward/record.url?scp=85105428292&partnerID=8YFLogxK
U2 - 10.1007/s11910-021-01123-0
DO - 10.1007/s11910-021-01123-0
M3 - Review article
C2 - 33956247
AN - SCOPUS:85105428292
SN - 1528-4042
VL - 21
JO - Current Neurology and Neuroscience Reports
JF - Current Neurology and Neuroscience Reports
IS - 7
M1 - 32
ER -