TY - JOUR
T1 - Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model
AU - Griffith, Matthew E.
AU - Moon, James E.
AU - Johnson, Erica N.
AU - Clark, Kyra P.
AU - Hawley, Joshua S.
AU - Hospenthal, Duane R.
AU - Murray, Clinton K.
PY - 2007/7
Y1 - 2007/7
N2 - Ciprofloxacin, gatifloxacin, and levofloxacin were evaluated for their abilities to prevent mortality in hamsters infected with a lethal inoculum of Leptospira interrogans serovar Portlandvere. Each agent produced a statistically significant survival advantage compared to no treatment and demonstrated survival similar to that seen with doxycycline therapy.
AB - Ciprofloxacin, gatifloxacin, and levofloxacin were evaluated for their abilities to prevent mortality in hamsters infected with a lethal inoculum of Leptospira interrogans serovar Portlandvere. Each agent produced a statistically significant survival advantage compared to no treatment and demonstrated survival similar to that seen with doxycycline therapy.
UR - http://www.scopus.com/inward/record.url?scp=34447261839&partnerID=8YFLogxK
U2 - 10.1128/AAC.00240-07
DO - 10.1128/AAC.00240-07
M3 - Article
C2 - 17470646
AN - SCOPUS:34447261839
SN - 0066-4804
VL - 51
SP - 2615
EP - 2617
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 7
ER -