Efficient quantification of HIV-1 in heparin plasma spiked with cultured HIV-1 by the roche cobas taqman and abbott realtime HIV-1 tests

Linda L. Jagodzinski*, Holly R. Weston, Ying Liu, Robert J. O'Connell, Sheila A. Peel

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The current automated real-time HIV-1 viral load assays, the Roche Cobas AmpliPrep/Cobas TaqMan test and the Abbott Real-Time test, are FDA cleared for use with EDTA plasma. We show that both real-time reverse transcription-PCR (RT-PCR) tests reliably quantify HIV-1 RNA in heparin plasma specimens spiked with HIV-1 isolate MN.

Original languageEnglish
Pages (from-to)2804-2806
Number of pages3
JournalJournal of Clinical Microbiology
Volume50
Issue number8
DOIs
StatePublished - Aug 2012
Externally publishedYes

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