Elastic modulus of prepared canine jejunum, a new vascular graft material

S. T. Herbert, S. F. Badylak*, L. A. Geddes, B. Hillberry, G. C. Lantz, K. Kokini

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


The submucosal connective tissue of the jejunum has been shown to be suitable for use as a vascular graft in preliminary dog studies. To partially characterize the mechanical properties of this new graft material, longitudinal stress (σ)-strain (ε)-data were obtained on 13 specimens of canine jejunum, stripped of its mucosal and external smooth-muscle layers. The ratio of stress to strain is the modulus of elasticity (E). It was found that the stress σ-strain ε-data fitted the expression γ=K∈α very well. For a typical specimen γ=2.69×1062.33. The modulus of elasticity (E=γ1-1/αK1/α) was found to increase with increasing stress, ranging from about 2,000 to 9,000 mmHg. For the average specimen E=573 γ0.57, where σ is in mmHg, (1 mmHg=133.3 Pascals).

Original languageEnglish
Pages (from-to)727-733
Number of pages7
JournalAnnals of Biomedical Engineering
Issue number6
StatePublished - Nov 1993
Externally publishedYes


  • Biomaterial
  • Mechanical properties
  • Vascular graft


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