Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Emil Lesho; Brendan Corey; Francois Lebreton; Ana C. Ong; Brett E. Swierczewski; Jason W. Bennett; Edward E. Walsh; Patrick McGann

doi:10.1093/cid/ciab507

Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Emil Lesho, Brendan Corey, Francois Lebreton, Ana C. Ong, Brett E. Swierczewski, Jason W. Bennett, Edward E. Walsh, Patrick McGann^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.

Original language	English
Pages (from-to)	909-912
Number of pages	4
Journal	Clinical Infectious Diseases
Volume	74
Issue number	5
DOIs	https://doi.org/10.1093/cid/ciab507
State	Published - 1 Mar 2022
Externally published	Yes

Keywords

E484K mutation
SARS-CoV-2
lineage B.1.1.345

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title = "Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York",

abstract = "A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.",

keywords = "E484K mutation, SARS-CoV-2, lineage B.1.1.345",

author = "Emil Lesho and Brendan Corey and Francois Lebreton and Ong, {Ana C.} and Swierczewski, {Brett E.} and Bennett, {Jason W.} and Walsh, {Edward E.} and Patrick McGann",

note = "Publisher Copyright: {\textcopyright} 2021 Published by Oxford University Press for the Infectious Diseases Society of America.",

year = "2022",

month = mar,

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doi = "10.1093/cid/ciab507",

language = "English",

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AU - Lesho, Emil

AU - Corey, Brendan

AU - Lebreton, Francois

AU - Ong, Ana C.

AU - Swierczewski, Brett E.

AU - Bennett, Jason W.

AU - Walsh, Edward E.

AU - McGann, Patrick

PY - 2022/3/1

Y1 - 2022/3/1

N2 - A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.

AB - A severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.345 variant carrying the E484K mutation was detected in 4 patients with no apparent epidemiological association from a hospital network in upstate New York. Subsequent analysis identified an additional 11 B.1.1.345 variants from this region between December 2020 and February 2021.

KW - E484K mutation

KW - SARS-CoV-2

KW - lineage B.1.1.345

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DO - 10.1093/cid/ciab507

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Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York

Abstract

Keywords

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