Emerging hemorrhage control and resuscitation strategies in trauma: Endovascular to extracorporeal

James E. Manning, Todd E. Rasmussen, Samuel A. Tisherman, Jeremy W. Cannon*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


This article reviews four emerging endovascular hemorrhage control and extracorporeal perfusion techniques for management of trauma patients with profound hemorrhagic shock including hemorrhage-induced traumatic cardiac arrest: resuscitative endovascular balloon occlusion of the aorta, selective aortic arch perfusion, extracorporeal life support, and emergency preservation and resuscitation. The preclinical and clinical studies underpinning each of these techniques are summarized. We also present an integrated conceptual framework for how these emerging technologies may be used in the future care of trauma patients in both resource-rich and austere environments.

Original languageEnglish
Pages (from-to)S50-S58
JournalJournal of Trauma and Acute Care Surgery
Issue number2
StatePublished - Aug 2020
Externally publishedYes


  • Endovascular techniques
  • balloon occlusion
  • extracorporeal life support
  • hemorrhagic shock
  • induced hypothermia


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