Equine cellular therapy-from stall to bench to bedside?

Janina Burk, Stephen F. Badylak, Jeremy Kelly, Walter Brehm*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


Pioneering clinical stem cell research is being performed in the horse, a recipient of cutting edge veterinary medicine as well as a unique animal model, paving the way for human medical applications. Although demonstrable progress has been made on the clinical front, in vitro characterization of equine stem cells is still in comparatively early stages. To translate the promising results of clinical stem cell therapy in the horse, advances must be made in the characterization of equine stem cells. Aiming to improve communication between veterinarians and other natural scientists, this review gives an overview of veterinary "bedside" achievements, focusing on stem cell therapies in equine orthopedics as well as the current state of in vitro characterization of equine multipotent mesenchymal stromal cells (MSCs) and equine embryonic stem cells (ESCs).

Original languageEnglish
Pages (from-to)103-113
Number of pages11
JournalCytometry Part A
Volume83 A
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • Cartilage
  • Embryonic stem cells
  • Horse
  • In vitro characterization
  • Mesenchymal stromal cells
  • Orthopedics
  • Tendon


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