Erratum: NETWORK ANALYSIS OF SINGLE-NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH ABERRANT INFLAMMATION IN TRAUMA PATIENTS SUGGESTS A ROLE FOR VESICLE-ASSOCIATED INFLAMMATORY PROGRAMS INVOLVING CD55 (Shock DOI: 10.1097/SHK.0000000000002448)

Herein, we report an error in our recently published manuscript entitled "Network analysis of single-nucleotide polymorphisms associated with aberrant inflammation in trauma patients suggests a role for vesicle-associated inflammatory programs involving CD55" DOI: 10.1097/SHK.0000000000002448). To analyze the control SNPs for significant differences (Table 2, Table 4, and Figure 3), we created a Python script which selected all SNPs from the SNPScanner results with zero statistically significant inflammatory biomarkers, compiled their data for clinical outcomes, and ran Mann-Whitney U tests for the two homozygous subgroups for each SNP. Here, an error was introduced in which the list of locations of the SNPs was sorted out of sync to the SNP names, and as consequence, the results for the outcome differences for the control SNPs did not correspond to the proper SNP. We discovered this error later and re-ran the script with the SNPs’ names properly linked to their location in the DataFrame. This new run produced 16 different control SNPs than those shown in Table 2, Table 4, and Figure 3. Despite this, the core findings remain the same (namely implicating phosphatidylinositol metabolites in the control group). Notably, as the script was only run on SNPs with no significantly different mediator differences, this error does not affect any of the analyses pertaining to altered inflammation SNPs. We have corrected these issues in the revised Table 2, Table 4, and Fig. 3). The corrected Python code has been uploaded to github at the following link: https://github.com/fayteneldehaibi/SNPScanner. (Figure presented).