TY - JOUR
T1 - Establishment of SARS-CoV-2 genomic surveillance within the Military Health System during 1 March-31 December 2020
AU - Morton, Lindsay
AU - Forshey, Brett
AU - Bishop-Lilly, Kimberly
AU - Cer, Regina
AU - Fries, Anthony
AU - Bogue, Amy
AU - Undewood, Ryan
AU - Bazaco, Sara
AU - Starr, Clarise
AU - Gruner, William
AU - Malagon, Francisco
AU - Myers, Christopher
AU - Maljkovic Berry, Irina
AU - Kugelman, Jeffrey
AU - Creppage, Kathleen
AU - Scheckelhoff, Mark
AU - Taylor, Kevin
AU - Pimentel, Guillermo
PY - 2022/7/1
Y1 - 2022/7/1
N2 - This report describes SARS-CoV-2 genomic surveillance conducted by the Department of Defense (DoD) Global Emerging Infections Surveillance Branch and the Next-Generation Sequencing and Bioinformatics Consortium (NGSBC) in response to the COVID-19 pandemic. Samples and sequence data were from SARS-CoV-2 infections occurring among Military Health System (MHS) beneficiaries from 1 March to 31 December 2020. There were 1,366 MHS samples sequenced from 10 countries, 36 U.S states or territories, and 5 Geographic Combatant Commands, representing approximately 2% of DoD cases in 2020. Genomes from these samples were compared with other public sequences; observed trends were similar to those of Centers for Disease Control and Prevention national surveillance in the U.S. with B.1, B.1.2, and other sub-lineages comprising the dominant variants of SARS-CoV-2. Sequence data were used to monitor transmission dynamics on U.S. Navy ships and at military training centers and installations. As new variants emerge, DoD medical and public health practitioners should maximize the use of genomic surveillance resources within DoD to inform force health protection measures.
AB - This report describes SARS-CoV-2 genomic surveillance conducted by the Department of Defense (DoD) Global Emerging Infections Surveillance Branch and the Next-Generation Sequencing and Bioinformatics Consortium (NGSBC) in response to the COVID-19 pandemic. Samples and sequence data were from SARS-CoV-2 infections occurring among Military Health System (MHS) beneficiaries from 1 March to 31 December 2020. There were 1,366 MHS samples sequenced from 10 countries, 36 U.S states or territories, and 5 Geographic Combatant Commands, representing approximately 2% of DoD cases in 2020. Genomes from these samples were compared with other public sequences; observed trends were similar to those of Centers for Disease Control and Prevention national surveillance in the U.S. with B.1, B.1.2, and other sub-lineages comprising the dominant variants of SARS-CoV-2. Sequence data were used to monitor transmission dynamics on U.S. Navy ships and at military training centers and installations. As new variants emerge, DoD medical and public health practitioners should maximize the use of genomic surveillance resources within DoD to inform force health protection measures.
KW - COVID-19/epidemiology
KW - Genomics
KW - Humans
KW - Military Health Services
KW - Military Personnel
KW - Pandemics
KW - SARS-CoV-2/genetics
M3 - Article
C2 - 36250580
SN - 2158-0111
VL - 29
SP - 11
EP - 18
JO - Medical Surveillance Monthly Report
JF - Medical Surveillance Monthly Report
IS - 7
ER -