Evaluation of a rapid assay for detection of Chlamydia trachomatis infections in outpatient clinics in South Kalimantan, Indonesia

Susana Widjaja; Surekha Cohen; William E. Brady; Kevin O'Reilly; Susanto; Ajar Wibowo; Cahyono; Robert R. Graham; Kevin R. Porter

doi:10.1128/jcm.37.12.4183-4185.1999

Evaluation of a rapid assay for detection of Chlamydia trachomatis infections in outpatient clinics in South Kalimantan, Indonesia

Susana Widjaja, Surekha Cohen, William E. Brady, Kevin O'Reilly, Susanto, Ajar Wibowo, Cahyono, Robert R. Graham, Kevin R. Porter

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14 Scopus citations

Abstract

A multicenter cross-sectional survey was conducted comparing a commercially available chlamydial optical immunoassay (OIA) to the chlamydial ligase chain reaction (LCR). Endocervical samples from 415 outpatients visiting clinics from three hospitals in South Kalimantan, Indonesia, were evaluated. Relative to the LCR, the overall sensitivity and specificity of the OIA were 31.6 and 98.9%, respectively. The sensitivity of the OIA varied among the three hospital laboratories, ranging from 20 to 50%. The OIA performance was slightly lower on samples from patients attending dermatovenereology clinics than on samples from nondermatovenereology clinic patients. The results indicate that the OIA did not perform well compared to LCR.

Original language	English
Pages (from-to)	4183-4185
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	37
Issue number	12
DOIs	https://doi.org/10.1128/jcm.37.12.4183-4185.1999
State	Published - Dec 1999
Externally published	Yes

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title = "Evaluation of a rapid assay for detection of Chlamydia trachomatis infections in outpatient clinics in South Kalimantan, Indonesia",

abstract = "A multicenter cross-sectional survey was conducted comparing a commercially available chlamydial optical immunoassay (OIA) to the chlamydial ligase chain reaction (LCR). Endocervical samples from 415 outpatients visiting clinics from three hospitals in South Kalimantan, Indonesia, were evaluated. Relative to the LCR, the overall sensitivity and specificity of the OIA were 31.6 and 98.9%, respectively. The sensitivity of the OIA varied among the three hospital laboratories, ranging from 20 to 50%. The OIA performance was slightly lower on samples from patients attending dermatovenereology clinics than on samples from nondermatovenereology clinic patients. The results indicate that the OIA did not perform well compared to LCR.",

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AU - Widjaja, Susana

AU - Cohen, Surekha

AU - Brady, William E.

AU - O'Reilly, Kevin

AU - Susanto,

AU - Wibowo, Ajar

AU - Cahyono,

AU - Graham, Robert R.

AU - Porter, Kevin R.

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AB - A multicenter cross-sectional survey was conducted comparing a commercially available chlamydial optical immunoassay (OIA) to the chlamydial ligase chain reaction (LCR). Endocervical samples from 415 outpatients visiting clinics from three hospitals in South Kalimantan, Indonesia, were evaluated. Relative to the LCR, the overall sensitivity and specificity of the OIA were 31.6 and 98.9%, respectively. The sensitivity of the OIA varied among the three hospital laboratories, ranging from 20 to 50%. The OIA performance was slightly lower on samples from patients attending dermatovenereology clinics than on samples from nondermatovenereology clinic patients. The results indicate that the OIA did not perform well compared to LCR.

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Evaluation of a rapid assay for detection of Chlamydia trachomatis infections in outpatient clinics in South Kalimantan, Indonesia

Abstract

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