Extended pancreatectomy with resection of the celiac axis: the modified Appleby operation

Singh Gagandeep, Avo Artinyan, Nicolas Jabbour, Rodrigo Mateo, Lea Matsuoka, Linda Sher, Yuri Genyk, Rick Selby*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

Background: Celiac axis invasion by central and distal pancreatic cancers has been considered a contraindication to resection. Appleby first described en-bloc celiac axis resection with total gastrectomy for locally advanced gastric cancer. We present our experience with a modification of this procedure in central pancreatic cancers involving the celiac trunk. Methods: Three patients with central pancreatic cancers invading the celiac axis are reviewed. All patients underwent extended pancreatectomy with en-bloc resection of the celiac axis. Results: Margins were grossly clear of tumor in all patients. The mean length of stay was 8.3 ± 1.1 days. There was no evidence of clinically significant gastric or hepatic ischemia. All 3 patients remain disease free at 34, 14, and 14 months from surgery, respectively. Comments: Extended pancreatectomy with celiac axis resection can result in prolonged survival and should be considered in central and distal pancreatic cancers invading the celiac trunk.

Original languageEnglish
Pages (from-to)330-335
Number of pages6
JournalAmerican Journal of Surgery
Volume192
Issue number3
DOIs
StatePublished - Sep 2006

Keywords

  • Celiac axis
  • Modified Appleby operation
  • Pancreatectomy
  • Pancreatic cancer

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