Extracellular matrix as a bioscaffold for tissue engineering

Brian M. Sicari; Ricardo Londono; Jenna L. Dziki; Stephen F. Badylak

doi:10.1016/B978-0-12-420145-3.00005-5

Extracellular matrix as a bioscaffold for tissue engineering

Brian M. Sicari
, Ricardo Londono
, Jenna L. Dziki
, Stephen F. Badylak

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

10 Scopus citations

Abstract

This chapter discusses mammalian extracellular matrix (ECM) as a biologic scaffold material for tissue engineering applications. ECM has been used as a surgically implantable bioscaffold for the reconstruction of injured or missing tissues. Biologic scaffolds composed of ECM alter the default mammalian injury response and promote constructive and functional tissue remodeling. This chapter reviews ECM bioscaffold preparation and mechanisms of action. Commercially available ECM bioscaffolds and recent clinical applications are also discussed.

Original language	English
Title of host publication	Tissue Engineering, Third Edition
Subtitle of host publication	Second Edition
Publisher	Elsevier
Pages	149-175
Number of pages	27
ISBN (Electronic)	9780128244593
ISBN (Print)	9780323851343
DOIs	https://doi.org/10.1016/B978-0-12-420145-3.00005-5 https://doi.org/10.1016/B978-0-12-824459-3.00005-6
State	Published - 10 Dec 2014
Externally published	Yes

Keywords

Biologic scaffolds
ECM Bioscaffolds
Extracellular matrix (ECM)
Regenerative medicine
Tissue engineering
Tissue remodeling

Access to Document

Cite this

@inbook{a0c12dbcaf3549e39d00b60ec84bb5e8,

title = "Extracellular matrix as a bioscaffold for tissue engineering",

abstract = "This chapter discusses mammalian extracellular matrix (ECM) as a biologic scaffold material for tissue engineering applications. ECM has been used as a surgically implantable bioscaffold for the reconstruction of injured or missing tissues. Biologic scaffolds composed of ECM alter the default mammalian injury response and promote constructive and functional tissue remodeling. This chapter reviews ECM bioscaffold preparation and mechanisms of action. Commercially available ECM bioscaffolds and recent clinical applications are also discussed.",

keywords = "Biologic scaffolds, ECM Bioscaffolds, Extracellular matrix (ECM), Regenerative medicine, Tissue engineering, Tissue remodeling",

author = "Sicari, \{Brian M.\} and Ricardo Londono and Dziki, \{Jenna L.\} and Badylak, \{Stephen F.\}",

year = "2014",

month = dec,

day = "10",

doi = "10.1016/B978-0-12-420145-3.00005-5",

language = "English",

isbn = "9780323851343",

pages = "149--175",

booktitle = "Tissue Engineering, Third Edition",

publisher = "Elsevier",

}

TY - CHAP

T1 - Extracellular matrix as a bioscaffold for tissue engineering

AU - Sicari, Brian M.

AU - Londono, Ricardo

AU - Dziki, Jenna L.

AU - Badylak, Stephen F.

PY - 2014/12/10

Y1 - 2014/12/10

N2 - This chapter discusses mammalian extracellular matrix (ECM) as a biologic scaffold material for tissue engineering applications. ECM has been used as a surgically implantable bioscaffold for the reconstruction of injured or missing tissues. Biologic scaffolds composed of ECM alter the default mammalian injury response and promote constructive and functional tissue remodeling. This chapter reviews ECM bioscaffold preparation and mechanisms of action. Commercially available ECM bioscaffolds and recent clinical applications are also discussed.

AB - This chapter discusses mammalian extracellular matrix (ECM) as a biologic scaffold material for tissue engineering applications. ECM has been used as a surgically implantable bioscaffold for the reconstruction of injured or missing tissues. Biologic scaffolds composed of ECM alter the default mammalian injury response and promote constructive and functional tissue remodeling. This chapter reviews ECM bioscaffold preparation and mechanisms of action. Commercially available ECM bioscaffolds and recent clinical applications are also discussed.

KW - Biologic scaffolds

KW - ECM Bioscaffolds

KW - Extracellular matrix (ECM)

KW - Regenerative medicine

KW - Tissue engineering

KW - Tissue remodeling

UR - https://www.scopus.com/pages/publications/85150102037

U2 - 10.1016/B978-0-12-420145-3.00005-5

DO - 10.1016/B978-0-12-420145-3.00005-5

M3 - Chapter

AN - SCOPUS:85150102037

SN - 9780323851343

SP - 149

EP - 175

BT - Tissue Engineering, Third Edition

PB - Elsevier

ER -

Extracellular matrix as a bioscaffold for tissue engineering

Abstract

Keywords

Access to Document

Fingerprint

Cite this