Extracellular matrix scaffold for myocardial repair

Stephen Badylak*, Robert Tullius, Robert Matheny

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


UBS and SIS were used as a scaffold for the repair of the right ventricular free wall and right ventricular outflow tract in a porcine animal model. Surgically-created, full-thickness defects in the right ventricle, were repaired with a single layer sheet of UBS or SIS. Animals were sacrificed at periods of time ranging from 6 weeks to 5 months post surgery. In vitro contractility tests showed that the remodeled tissue could generate contractile forces up to 70% of that produced by native myocardium.

Original languageEnglish
Pages (from-to)S-119
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - 2000
Externally publishedYes
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: 12 Oct 200014 Oct 2000


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