Extracorporeal blood purification in burns: A review

Katharina Linden; Ian J. Stewart; Stefan F.X. Kreyer; Vittorio Scaravilli; Jeremy W. Cannon; Leopoldo C. Cancio; Andriy I. Batchinsky; Kevin K. Chung

doi:10.1016/j.burns.2014.01.013

Extracorporeal blood purification in burns: A review

Katharina Linden^*, Ian J. Stewart, Stefan F.X. Kreyer, Vittorio Scaravilli, Jeremy W. Cannon, Leopoldo C. Cancio, Andriy I. Batchinsky, Kevin K. Chung

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

Abstract

A prolonged and fulminant inflammatory state, with high levels of pro- and anti-inflammatory mediators, is seen after extensive thermal injury. Blood purification techniques including plasma exchange, continuous venovenous hemofiltration, and adsorbing membranes have the potential to modulate this response, thereby improving outcomes. This article describes the scientific rationale behind blood purification in burns and offers a review of literature regarding its potential application in this patient cohort.

Original language	English
Pages (from-to)	1071-1078
Number of pages	8
Journal	Burns
Volume	40
Issue number	6
DOIs	https://doi.org/10.1016/j.burns.2014.01.013
State	Published - Sep 2014
Externally published	Yes

Keywords

Blood purification
Burns
Cytokine removal
Thermal injury

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10.1016/j.burns.2014.01.013

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title = "Extracorporeal blood purification in burns: A review",

abstract = "A prolonged and fulminant inflammatory state, with high levels of pro- and anti-inflammatory mediators, is seen after extensive thermal injury. Blood purification techniques including plasma exchange, continuous venovenous hemofiltration, and adsorbing membranes have the potential to modulate this response, thereby improving outcomes. This article describes the scientific rationale behind blood purification in burns and offers a review of literature regarding its potential application in this patient cohort.",

keywords = "Blood purification, Burns, Cytokine removal, Thermal injury",

author = "Katharina Linden and Stewart, {Ian J.} and Kreyer, {Stefan F.X.} and Vittorio Scaravilli and Cannon, {Jeremy W.} and Cancio, {Leopoldo C.} and Batchinsky, {Andriy I.} and Chung, {Kevin K.}",

note = "Funding Information: This research was supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Institute of Surgical Research (USAISR) administered by Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USAMRMC.",

year = "2014",

month = sep,

doi = "10.1016/j.burns.2014.01.013",

language = "English",

volume = "40",

pages = "1071--1078",

journal = "Burns",

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TY - JOUR

T1 - Extracorporeal blood purification in burns

T2 - A review

AU - Linden, Katharina

AU - Stewart, Ian J.

AU - Kreyer, Stefan F.X.

AU - Scaravilli, Vittorio

AU - Cannon, Jeremy W.

AU - Cancio, Leopoldo C.

AU - Batchinsky, Andriy I.

AU - Chung, Kevin K.

N1 - Funding Information: This research was supported in part by an appointment to the Postgraduate Research Participation Program at the U.S. Army Institute of Surgical Research (USAISR) administered by Oak Ridge Institute for Science and Education through an interagency agreement between the U.S. Department of Energy and USAMRMC.

PY - 2014/9

Y1 - 2014/9

N2 - A prolonged and fulminant inflammatory state, with high levels of pro- and anti-inflammatory mediators, is seen after extensive thermal injury. Blood purification techniques including plasma exchange, continuous venovenous hemofiltration, and adsorbing membranes have the potential to modulate this response, thereby improving outcomes. This article describes the scientific rationale behind blood purification in burns and offers a review of literature regarding its potential application in this patient cohort.

AB - A prolonged and fulminant inflammatory state, with high levels of pro- and anti-inflammatory mediators, is seen after extensive thermal injury. Blood purification techniques including plasma exchange, continuous venovenous hemofiltration, and adsorbing membranes have the potential to modulate this response, thereby improving outcomes. This article describes the scientific rationale behind blood purification in burns and offers a review of literature regarding its potential application in this patient cohort.

KW - Blood purification

KW - Burns

KW - Cytokine removal

KW - Thermal injury

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U2 - 10.1016/j.burns.2014.01.013

DO - 10.1016/j.burns.2014.01.013

M3 - Review article

C2 - 24548734

AN - SCOPUS:84906789798

SN - 0305-4179

VL - 40

SP - 1071

EP - 1078

JO - Burns

JF - Burns

IS - 6

ER -

Extracorporeal blood purification in burns: A review

Abstract

Keywords

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