@article{016ce80ad49543de8f602220a2696295,
title = "Factor VIII: Perspectives on Immunogenicity and Tolerogenic Strategies",
abstract = "Therapeutic treatment of bleeds with FVIII can lead to an antibody response that effectively inhibits its function. Herein, we review the factors that contribute to this immunogenicity and possible ways to overcome it.",
keywords = "factor VIII, hemophilia, inhibitors, regulatory T (Treg) cells, tolerance",
author = "Scott, {David W.} and Pratt, {Kathleen P.}",
note = "Funding Information: Funding. The research in the authors' laboratories was supported by grants from the NIH [RO1 HL126727 (DS), HL130448 (KP)], and the National Multiple Sclerosis Society. Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2020 Scott and Pratt.",
year = "2020",
month = jan,
day = "17",
doi = "10.3389/fimmu.2019.03078",
language = "English",
volume = "10",
journal = "Frontiers in Immunology",
issn = "1664-3224",
}