Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque

M. Song; M. S. Mulvihill; K. D. Williams; B. H. Collins; A. D. Kirk

doi:10.1111/jmp.12285

Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque

M. Song, M. S. Mulvihill^*, K. D. Williams, B. H. Collins, A. D. Kirk

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.

Original language	English
Pages (from-to)	81-84
Number of pages	4
Journal	Journal of Medical Primatology
Volume	47
Issue number	1
DOIs	https://doi.org/10.1111/jmp.12285
State	Published - Feb 2018
Externally published	Yes

Keywords

SV40
opportunistic infection
renal transplant
rhesus macaque
viral reactivation

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10.1111/jmp.12285

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title = "Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque",

abstract = "Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.",

keywords = "SV40, opportunistic infection, renal transplant, rhesus macaque, viral reactivation",

author = "M. Song and Mulvihill, {M. S.} and Williams, {K. D.} and Collins, {B. H.} and Kirk, {A. D.}",

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AU - Collins, B. H.

AU - Kirk, A. D.

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N2 - Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.

AB - Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.

KW - SV40

KW - opportunistic infection

KW - renal transplant

KW - rhesus macaque

KW - viral reactivation

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Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque

Abstract

Keywords

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