From Discovery to Practice and Survivorship: Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients

TY - JOUR

T1 - From Discovery to Practice and Survivorship

T2 - Building a National Real-World Data Learning Healthcare Framework for Military and Veteran Cancer Patients

AU - Lee, Jerry S.H.

AU - Darcy, Kathleen M.

AU - Hu, Hai

AU - Casablanca, Yovanni

AU - Conrads, Thomas P.

AU - Dalgard, Clifton L.

AU - Freymann, John B.

AU - Hanlon, Sean E.

AU - Huang, Grant D.

AU - Kvecher, Leonid

AU - Maxwell, George L.

AU - Meng, Frank

AU - Moncur, Joel T.

AU - Turner, Clesson

AU - Wells, Justin M.

AU - Wilkerson, Matthew D.

AU - Zhu, Kangmin

AU - Ramoni, Rachel B.

AU - Shriver, Craig D.

N1 - Funding Information: Funding for these efforts was provided from Uniformed Services University of the Health Sciences (USUHS) awards from the Defense Health Program to the Murtha Cancer Center Research Program (HU0001-16-2-0014, C.D. Shriver and J.S.H. Lee), the Gynecologic Cancer Center of Excellence (HU0001-16-2-0006, Y. Casablanca and G. Larry Maxwell), and HU0001-16-2-004 (L. Kvecher and H. Hu) administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine. This project has also been funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261200800001E (J.B. Freymann). Funding Information: 1Department of Medicine/Oncology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA; 2Department of Chemical Engineering and Material Science, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA; 3Lawrence J. Ellison Institute for Transformative Medicine, University of Southern California, Los Angeles, California, USA; 4Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, USA; 5Center for Strategic Scientific Initiatives, National Cancer Institute, Bethesda, Maryland, USA; 6Office of Research and Development, Department of Veterans Affairs, Washington, DC, USA; 7Department of Obstetrics & Gynecology, Gynecologic Cancer Center of Excellence, Uniformed Services University of the Health Sciences and Walter Reed National Military Medical Center, Bethesda, Maryland, USA; 8John P. Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences and Walter Reed National Military Medical Center, Bethesda, Maryland, USA; 9Chan Soon-Shiong Institute of Molecular Medicine at Windber, Windber, Pennsylvania, USA; 10Department of Obstetrics and Gynecology, Inova Schar Cancer Institute, Inova Fairfax Hospital, Falls Church, Virginia, USA; 11Department of Anatomy, Physiology, and Genetics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA; 12The American Genome Center, Collaborative Health Initiative Research Program, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA; 13Cancer Imaging Informatics Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA; 14Massachusetts Veterans Epidemiology Research and Information Center, Veterans Affairs Boston Healthcare, Boston, Massachusetts, USA; 15Department of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA; 16Joint Pathology Center, National Capital Region Medical Directorate, Defense Health Agency, Silver Spring, Maryland, USA; 17Department of Pediatrics, Division of Genetics, Walter Reed National Military Medical Center, Bethesda, Maryland, USA; 18Department of Pathology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA; 19Department of Surgery, Uniformed Services University of the Health Sciences and Walter Reed National Military Medical Center, Bethesda, Maryland, USA. *Correspondence: Jerry S.H. Lee ([email protected]) and Craig D. Shriver ([email protected]) Funding Information: Funding for these efforts was provided from Uniformed Services University of the Health Sciences (USUHS) awards from the Defense Health Program to the Murtha Cancer Center Research Program (HU0001-16-2-0014, C.D. Shriver and J.S.H. Lee), the Gynecologic Cancer Center of Excellence (HU0001-16-2-0006, Y. Casablanca and G. Larry Maxwell), and HU0001-16-2-004 (L. Kvecher and H. Hu) administered by the Henry M. Jackson Foundation for the Advancement of Military Medicine. This project has also been funded in whole or in part with federal funds from the National Cancer Institute, National Institutes of Health, under Contract No. HHSN261200800001E (J.B. Freymann). The authors would like to thank Joseph Shaw, Sara Sakura, Autumn Beemer Phillips, Gregory Samuel, Olga Castellanos, Jillian Infusino, and Mayada Aljehani for their critical review of the figure and paper.

PY - 2019/7

Y1 - 2019/7

UR - https://www.scopus.com/pages/publications/85065196929

U2 - 10.1002/cpt.1425

DO - 10.1002/cpt.1425

M3 - Comment/debate

C2 - 30838639

AN - SCOPUS:85065196929

SN - 0009-9236

VL - 106

SP - 52

EP - 57

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

IS - 1

ER -