Genome-scale, functional screen of Plasmodium sexual replication

Surendra K. Prajapati, Kim C. Williamson*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

1 Scopus citations

Abstract

Malaria mortality remains above 500 000 people annually, demonstrating the need for new and innovative control approaches. Using a genome-scale, functional screen of Plasmodium sexual replication, Sayers et al. identified over 300 genes essential for malaria transmission through the mosquito, providing many new candidates for drug and vaccine development.

Original languageEnglish
Pages (from-to)80-82
Number of pages3
JournalTrends in Parasitology
Volume41
Issue number2
DOIs
StatePublished - Feb 2025
Externally publishedYes

Keywords

  • axoneme
  • fertilization
  • gametogenesis
  • malaria transmission
  • mitochondria
  • SUN1

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