Abstract
Malaria mortality remains above 500 000 people annually, demonstrating the need for new and innovative control approaches. Using a genome-scale, functional screen of Plasmodium sexual replication, Sayers et al. identified over 300 genes essential for malaria transmission through the mosquito, providing many new candidates for drug and vaccine development.
| Original language | English |
|---|---|
| Pages (from-to) | 80-82 |
| Number of pages | 3 |
| Journal | Trends in Parasitology |
| Volume | 41 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2025 |
Keywords
- SUN1
- axoneme
- fertilization
- gametogenesis
- malaria transmission
- mitochondria
- Animals
- Malaria/transmission
- Humans
- Plasmodium/genetics
- Reproduction/genetics
- Genome, Protozoan/genetics
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