Genomic-scale analysis of gene expression in resting and activated T cells

Philippa Marrack; Tom Mitchell; David Hildeman; Ross Kedl; T. Kent Teague; Jeremy Bender; William Rees; Brian C. Schaefer; John Kappler

doi:10.1016/S0952-7915(99)00075-8

Genomic-scale analysis of gene expression in resting and activated T cells

Philippa Marrack^*, Tom Mitchell, David Hildeman, Ross Kedl, T. Kent Teague, Jeremy Bender, William Rees, Brian C. Schaefer, John Kappler

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

48 Scopus citations

Abstract

Recent advances in gene array technology and isolation of lymphocytes now allow comprehensive analysis of gene expression in many different types of T cells. So far only a few sets of results have been published. However it is already clear that these analyses provide accurate measurements of gene expression in T cells. This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli.

Original language	English
Pages (from-to)	206-209
Number of pages	4
Journal	Current Opinion in Immunology
Volume	12
Issue number	2
DOIs	https://doi.org/10.1016/S0952-7915(99)00075-8
State	Published - 1 Apr 2000
Externally published	Yes

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10.1016/S0952-7915(99)00075-8

Cite this

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title = "Genomic-scale analysis of gene expression in resting and activated T cells",

abstract = "Recent advances in gene array technology and isolation of lymphocytes now allow comprehensive analysis of gene expression in many different types of T cells. So far only a few sets of results have been published. However it is already clear that these analyses provide accurate measurements of gene expression in T cells. This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli.",

author = "Philippa Marrack and Tom Mitchell and David Hildeman and Ross Kedl and Teague, {T. Kent} and Jeremy Bender and William Rees and Schaefer, {Brian C.} and John Kappler",

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AU - Mitchell, Tom

AU - Hildeman, David

AU - Kedl, Ross

AU - Teague, T. Kent

AU - Bender, Jeremy

AU - Rees, William

AU - Schaefer, Brian C.

AU - Kappler, John

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AB - Recent advances in gene array technology and isolation of lymphocytes now allow comprehensive analysis of gene expression in many different types of T cells. So far only a few sets of results have been published. However it is already clear that these analyses provide accurate measurements of gene expression in T cells. This technology offers the first opportunity to examine global and subtle changes in gene expression in response to specific stimuli.

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DO - 10.1016/S0952-7915(99)00075-8

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