Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity

Eric J. Ormseth; Kent C. Holtzmuller; Zachary D. Goodman; John O. Colonna; Donald S. Batty; Maria H. Sjogren

doi:10.1016/S0002-9270(01)02369-3

Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity

Eric J. Ormseth, Kent C. Holtzmuller^*, Zachary D. Goodman, John O. Colonna, Donald S. Batty, Maria H. Sjogren

^*Corresponding author for this work

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16 Scopus citations

Abstract

We report a case of a 62-yr-old man with chronic hepatitis B virus (HBV)-related cirrhosis who developed hepatic decompensation after being started on lamivudine requiring liver transplantation. Decompensated liver disease while on lamivudine has been previously reported on two occasions, both HIV coinfected patients on a combination of nucleoside analogues. Our patient is alive and well nearly 2 yr after successful liver transplantation.

Original language	English
Pages (from-to)	1619-1622
Number of pages	4
Journal	American Journal of Gastroenterology
Volume	96
Issue number	5
DOIs	https://doi.org/10.1016/S0002-9270(01)02369-3
State	Published - May 2001
Externally published	Yes

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title = "Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity",

abstract = "We report a case of a 62-yr-old man with chronic hepatitis B virus (HBV)-related cirrhosis who developed hepatic decompensation after being started on lamivudine requiring liver transplantation. Decompensated liver disease while on lamivudine has been previously reported on two occasions, both HIV coinfected patients on a combination of nucleoside analogues. Our patient is alive and well nearly 2 yr after successful liver transplantation.",

author = "Ormseth, {Eric J.} and Holtzmuller, {Kent C.} and Goodman, {Zachary D.} and Colonna, {John O.} and Batty, {Donald S.} and Sjogren, {Maria H.}",

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AU - Colonna, John O.

AU - Batty, Donald S.

AU - Sjogren, Maria H.

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AB - We report a case of a 62-yr-old man with chronic hepatitis B virus (HBV)-related cirrhosis who developed hepatic decompensation after being started on lamivudine requiring liver transplantation. Decompensated liver disease while on lamivudine has been previously reported on two occasions, both HIV coinfected patients on a combination of nucleoside analogues. Our patient is alive and well nearly 2 yr after successful liver transplantation.

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ER -

Hepatic decompensation associated with lamivudine: A case report and review of lamivudine-induced hepatotoxicity

Abstract

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