Using phonocardiography and auscultation, we ascertained the presence or absence of hepatojugular reflux and Carvallo's maneuver in three groups of 15 patients. The first group had isolated tricuspid regurgitation; the second, isolated mitral regurgitation; and the third was a control group with no murmurs. The specificity and sensitivity of hepatojugular reflux were 100% and 66%, and those of Carvallo's maneuver were 100% and 80%. All but 1 patient in our series had a positive response to one or the other maneuver (combined sensitivity, 93%). Thus, hepatojugular reflux is a useful adjunct to Carvallo's maneuver in the diagnosis of tricuspid regurgitation.