Heterotopic ossification in orthopaedic trauma

Aaron Nauth; Erica Giles; Benjamin K. Potter; Leon J. Nesti; Frederick P. O'Brien; Michael J. Bosse; Jeffrey O. Anglen; Samir Mehta; Jaimo Ahn; Theodore Miclau; Emil H. Schemitsch

doi:10.1097/BOT.0b013e3182724624

Heterotopic ossification in orthopaedic trauma

Aaron Nauth, Erica Giles, Benjamin K. Potter, Leon J. Nesti, Frederick P. O'Brien, Michael J. Bosse, Jeffrey O. Anglen, Samir Mehta, Jaimo Ahn, Theodore Miclau, Emil H. Schemitsch^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

111 Scopus citations

Abstract

Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

Original language	English
Pages (from-to)	684-688
Number of pages	5
Journal	Journal of Orthopaedic Trauma
Volume	26
Issue number	12
DOIs	https://doi.org/10.1097/BOT.0b013e3182724624
State	Published - Dec 2012
Externally published	Yes

Keywords

NSAIDs
blast injuries
heterotopic ossification
pathophysiology
prophylaxis
radiation therapy
spinal cord injury
surgical treatment
traumatic brain injury

Access to Document

10.1097/BOT.0b013e3182724624

Cite this

@article{54aab6f530ec42259ad45ec4af0ebb9a,

title = "Heterotopic ossification in orthopaedic trauma",

abstract = "Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.",

keywords = "NSAIDs, blast injuries, heterotopic ossification, pathophysiology, prophylaxis, radiation therapy, spinal cord injury, surgical treatment, traumatic brain injury",

author = "Aaron Nauth and Erica Giles and Potter, {Benjamin K.} and Nesti, {Leon J.} and O'Brien, {Frederick P.} and Bosse, {Michael J.} and Anglen, {Jeffrey O.} and Samir Mehta and Jaimo Ahn and Theodore Miclau and Schemitsch, {Emil H.}",

year = "2012",

month = dec,

doi = "10.1097/BOT.0b013e3182724624",

language = "English",

volume = "26",

pages = "684--688",

journal = "Journal of Orthopaedic Trauma",

issn = "0890-5339",

number = "12",

}

TY - JOUR

T1 - Heterotopic ossification in orthopaedic trauma

AU - Nauth, Aaron

AU - Giles, Erica

AU - Potter, Benjamin K.

AU - Nesti, Leon J.

AU - O'Brien, Frederick P.

AU - Bosse, Michael J.

AU - Anglen, Jeffrey O.

AU - Mehta, Samir

AU - Ahn, Jaimo

AU - Miclau, Theodore

AU - Schemitsch, Emil H.

PY - 2012/12

Y1 - 2012/12

N2 - Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

AB - Heterotopic ossification (HO) can be defined as the pathologic formation of bone in extraskeletal tissues. There has been a substantial amount of recent research on the pathophysiology, prophylaxis, and treatment of HO and traumatic conditions associated with the development of HO. This research has advanced our understanding of this disease and helped to clarify evidence-based approaches to both the prophylaxis and treatment of HO. This article reviews the literature on these topics with a focus on their application in orthopaedic trauma.

KW - NSAIDs

KW - blast injuries

KW - heterotopic ossification

KW - pathophysiology

KW - prophylaxis

KW - radiation therapy

KW - spinal cord injury

KW - surgical treatment

KW - traumatic brain injury

UR - http://www.scopus.com/inward/record.url?scp=84870250214&partnerID=8YFLogxK

U2 - 10.1097/BOT.0b013e3182724624

DO - 10.1097/BOT.0b013e3182724624

M3 - Article

C2 - 23010648

AN - SCOPUS:84870250214

SN - 0890-5339

VL - 26

SP - 684

EP - 688

JO - Journal of Orthopaedic Trauma

JF - Journal of Orthopaedic Trauma

IS - 12

ER -

Heterotopic ossification in orthopaedic trauma

Abstract

Keywords

Access to Document

Fingerprint

Cite this