TY - JOUR
T1 - History of infections associated with combat-related injuries
AU - Murray, Clinton K.
AU - Hinkle, Mary K.
AU - Yun, Heather C.
PY - 2008/3
Y1 - 2008/3
N2 - Despite the innumerable variations in war-making throughout the millennia, wounds have always been characterized by devitalized tissue, the presence of foreign bodies, clots, fluid collection, and contamination by microorganisms. Even in the postantibiotic era, infections of these wounds remain a significant contributor to both morbidity and mortality. Shifts in causal organisms and their resistance profiles continue to challenge each new generation of therapeutics. This article reviews the history of war wound infections, with an emphasis on wound microbiology and combat casualty management during US conflicts from World War I through the end of 20th century.
AB - Despite the innumerable variations in war-making throughout the millennia, wounds have always been characterized by devitalized tissue, the presence of foreign bodies, clots, fluid collection, and contamination by microorganisms. Even in the postantibiotic era, infections of these wounds remain a significant contributor to both morbidity and mortality. Shifts in causal organisms and their resistance profiles continue to challenge each new generation of therapeutics. This article reviews the history of war wound infections, with an emphasis on wound microbiology and combat casualty management during US conflicts from World War I through the end of 20th century.
KW - Combat
KW - History
KW - Infection
UR - http://www.scopus.com/inward/record.url?scp=43149124640&partnerID=8YFLogxK
U2 - 10.1097/TA.0b013e318163c40b
DO - 10.1097/TA.0b013e318163c40b
M3 - Article
C2 - 18316966
AN - SCOPUS:43149124640
SN - 0022-5282
VL - 64
SP - S221-S231
JO - Journal of Trauma - Injury, Infection and Critical Care
JF - Journal of Trauma - Injury, Infection and Critical Care
IS - SUPPL. 3
ER -