Immunogenicity of a psoralen-inactivated dengue virus type 1 vaccine candidate in mice

Ryan C. Maves; Roger M. Castillo Oré; Kevin R. Porter; Tadeusz J. Kochel

doi:10.1128/CVI.00353-09

Immunogenicity of a psoralen-inactivated dengue virus type 1 vaccine candidate in mice

Ryan C. Maves, Roger M. Castillo Oré, Kevin R. Porter, Tadeusz J. Kochel

Medicine

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We evaluated a novel psoralen-inactivated dengue virus type 1 (DENV-1) vaccine candidate in Mus musculus mice. Mice received intradermal alum or 5 to 10 ng of psoralen-inactivated virus. Anti-DENV-1 neutralizing antibody was detectable in 10/11 mice receiving a 10-ng dose at 90 days. Psoralen-inactivated DENV-1 is immunogenic in mice.

Original language	English
Pages (from-to)	304-306
Number of pages	3
Journal	Clinical and Vaccine Immunology
Volume	17
Issue number	2
DOIs	https://doi.org/10.1128/CVI.00353-09
State	Published - Feb 2010

Access to Document

10.1128/CVI.00353-09

Cite this

@article{78e7422fc0694e3ab35e905e0192bbe8,

title = "Immunogenicity of a psoralen-inactivated dengue virus type 1 vaccine candidate in mice",

abstract = "We evaluated a novel psoralen-inactivated dengue virus type 1 (DENV-1) vaccine candidate in Mus musculus mice. Mice received intradermal alum or 5 to 10 ng of psoralen-inactivated virus. Anti-DENV-1 neutralizing antibody was detectable in 10/11 mice receiving a 10-ng dose at 90 days. Psoralen-inactivated DENV-1 is immunogenic in mice.",

author = "Maves, {Ryan C.} and {Castillo Or{\'e}}, {Roger M.} and Porter, {Kevin R.} and Kochel, {Tadeusz J.}",

year = "2010",

month = feb,

doi = "10.1128/CVI.00353-09",

language = "English",

volume = "17",

pages = "304--306",

journal = "Clinical and Vaccine Immunology",

issn = "1556-6811",

publisher = "American Society for Microbiology",

number = "2",

}

TY - JOUR

T1 - Immunogenicity of a psoralen-inactivated dengue virus type 1 vaccine candidate in mice

AU - Maves, Ryan C.

AU - Castillo Oré, Roger M.

AU - Porter, Kevin R.

AU - Kochel, Tadeusz J.

PY - 2010/2

Y1 - 2010/2

N2 - We evaluated a novel psoralen-inactivated dengue virus type 1 (DENV-1) vaccine candidate in Mus musculus mice. Mice received intradermal alum or 5 to 10 ng of psoralen-inactivated virus. Anti-DENV-1 neutralizing antibody was detectable in 10/11 mice receiving a 10-ng dose at 90 days. Psoralen-inactivated DENV-1 is immunogenic in mice.

AB - We evaluated a novel psoralen-inactivated dengue virus type 1 (DENV-1) vaccine candidate in Mus musculus mice. Mice received intradermal alum or 5 to 10 ng of psoralen-inactivated virus. Anti-DENV-1 neutralizing antibody was detectable in 10/11 mice receiving a 10-ng dose at 90 days. Psoralen-inactivated DENV-1 is immunogenic in mice.

UR - http://www.scopus.com/inward/record.url?scp=75749135300&partnerID=8YFLogxK

U2 - 10.1128/CVI.00353-09

DO - 10.1128/CVI.00353-09

M3 - Article

C2 - 20007362

AN - SCOPUS:75749135300

SN - 1556-6811

VL - 17

SP - 304

EP - 306

JO - Clinical and Vaccine Immunology

JF - Clinical and Vaccine Immunology

IS - 2

ER -

Immunogenicity of a psoralen-inactivated dengue virus type 1 vaccine candidate in mice

Abstract

Access to Document

Fingerprint

Cite this