Improvements in Virologic Control Among PWH Over Time: Narrowing the Gap Between Those With and Without STIs

the DC Cohort Executive Committee

doi:10.1007/s10461-022-03802-6

Improvements in Virologic Control Among PWH Over Time: Narrowing the Gap Between Those With and Without STIs

the DC Cohort Executive Committee

Graduate School of Nursing

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Using the incidence of bacterial sexually transmitted infection (STI) as a surrogate for condomless sexual behavior, we assessed the association between STI and uncontrolled HIV replication among in-care persons with HIV (PWH) enrolled in a longitudinal HIV cohort study in the District of Columbia (the DC Cohort). Although STI occurrence initially correlated with higher HIV viral load (VL), this difference became more attenuated over time (2012–2016). This was true overall and among those with the greatest number of STIs [age 18–34, men who have sex with men (MSM)]. This likely reflects gains in population-wide virologic control through improved antiretroviral therapy and access to care, which helps mitigate the risk of HIV transmission.

Original language	English
Pages (from-to)	673-677
Number of pages	5
Journal	AIDS and Behavior
Volume	27
Issue number	2
DOIs	https://doi.org/10.1007/s10461-022-03802-6
State	Published - Feb 2023

Keywords

Ending the HIV Epidemic
HIV
HIV transmission
Sexually transmitted infection
Viral load

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10.1007/s10461-022-03802-6

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title = "Improvements in Virologic Control Among PWH Over Time: Narrowing the Gap Between Those With and Without STIs",

abstract = "Using the incidence of bacterial sexually transmitted infection (STI) as a surrogate for condomless sexual behavior, we assessed the association between STI and uncontrolled HIV replication among in-care persons with HIV (PWH) enrolled in a longitudinal HIV cohort study in the District of Columbia (the DC Cohort). Although STI occurrence initially correlated with higher HIV viral load (VL), this difference became more attenuated over time (2012–2016). This was true overall and among those with the greatest number of STIs [age 18–34, men who have sex with men (MSM)]. This likely reflects gains in population-wide virologic control through improved antiretroviral therapy and access to care, which helps mitigate the risk of HIV transmission.",

keywords = "Ending the HIV Epidemic, HIV, HIV transmission, Sexually transmitted infection, Viral load",

author = "\{the DC Cohort Executive Committee\} and Hana Akselrod and Morgan Byrne and Jeannette Lundberg and Czeresnia, \{Jonathan Mamber\} and Jose Lucar and Alessandra Secco and Matt Levy and Anne Monroe and Amanda Castel and Michael Horberg and Rupali Doshi and Heather Rivasplata and Leah Squires and David Parenti and Debra Benator and Lawrence D{\textquoteright}Angelo and Natella Rakhmanina and Michael Kharfen and Michael Serlin and Princy Kumar and Vinay Bhandaru and Tsedenia Bezabeh and Nisha Grover-Fairchild and Lisa Mele and Susan Reamer and Alla Sapozhnikova and Greg Strylewicz and Marinella Temprosa and Naji Younes and Kevin Xiao and Morgan Byrne and Amanda Castel and Alan Greenberg and Maria Jaurretche and Paige Kulie and Anne Monroe and James Peterson and Bianca Stewart and Brittany Wilbourn and Yan Ma and Hana Akselrod and Gajjala, \{Jhansi L.\} and Sohail Rana and Michael Horberg and Ricardo Fernandez and Annick Hebou and Carl Dieffenbach and Henry Masur and Jose Bordon and Gebeyehu Teferi",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2023",

month = feb,

doi = "10.1007/s10461-022-03802-6",

language = "English",

volume = "27",

pages = "673--677",

journal = "AIDS and Behavior",

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AU - Lucar, Jose

AU - Secco, Alessandra

AU - Levy, Matt

AU - Monroe, Anne

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AU - Doshi, Rupali

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AU - Benator, Debra

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AU - Rakhmanina, Natella

AU - Kharfen, Michael

AU - Serlin, Michael

AU - Kumar, Princy

AU - Bhandaru, Vinay

AU - Bezabeh, Tsedenia

AU - Grover-Fairchild, Nisha

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AU - Reamer, Susan

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AU - Byrne, Morgan

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AU - Greenberg, Alan

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AU - Peterson, James

AU - Stewart, Bianca

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AU - Ma, Yan

AU - Akselrod, Hana

AU - Gajjala, Jhansi L.

AU - Rana, Sohail

AU - Horberg, Michael

AU - Fernandez, Ricardo

AU - Hebou, Annick

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AU - Bordon, Jose

AU - Teferi, Gebeyehu

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KW - Ending the HIV Epidemic

KW - HIV

KW - HIV transmission

KW - Sexually transmitted infection

KW - Viral load

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JO - AIDS and Behavior

JF - AIDS and Behavior

IS - 2

ER -

Improvements in Virologic Control Among PWH Over Time: Narrowing the Gap Between Those With and Without STIs

Abstract

Keywords

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