TY - JOUR
T1 - Improvements in Virologic Control Among PWH Over Time
T2 - Narrowing the Gap Between Those With and Without STIs
AU - the DC Cohort Executive Committee
AU - Akselrod, Hana
AU - Byrne, Morgan
AU - Lundberg, Jeannette
AU - Czeresnia, Jonathan Mamber
AU - Lucar, Jose
AU - Secco, Alessandra
AU - Levy, Matt
AU - Monroe, Anne
AU - Castel, Amanda
AU - Horberg, Michael
AU - Doshi, Rupali
AU - Rivasplata, Heather
AU - Squires, Leah
AU - Parenti, David
AU - Benator, Debra
AU - D’Angelo, Lawrence
AU - Rakhmanina, Natella
AU - Kharfen, Michael
AU - Serlin, Michael
AU - Kumar, Princy
AU - Bhandaru, Vinay
AU - Bezabeh, Tsedenia
AU - Grover-Fairchild, Nisha
AU - Mele, Lisa
AU - Reamer, Susan
AU - Sapozhnikova, Alla
AU - Strylewicz, Greg
AU - Temprosa, Marinella
AU - Younes, Naji
AU - Xiao, Kevin
AU - Byrne, Morgan
AU - Castel, Amanda
AU - Greenberg, Alan
AU - Jaurretche, Maria
AU - Kulie, Paige
AU - Monroe, Anne
AU - Peterson, James
AU - Stewart, Bianca
AU - Wilbourn, Brittany
AU - Ma, Yan
AU - Akselrod, Hana
AU - Gajjala, Jhansi L.
AU - Rana, Sohail
AU - Horberg, Michael
AU - Fernandez, Ricardo
AU - Hebou, Annick
AU - Dieffenbach, Carl
AU - Masur, Henry
AU - Bordon, Jose
AU - Teferi, Gebeyehu
N1 - Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2023/2
Y1 - 2023/2
N2 - Using the incidence of bacterial sexually transmitted infection (STI) as a surrogate for condomless sexual behavior, we assessed the association between STI and uncontrolled HIV replication among in-care persons with HIV (PWH) enrolled in a longitudinal HIV cohort study in the District of Columbia (the DC Cohort). Although STI occurrence initially correlated with higher HIV viral load (VL), this difference became more attenuated over time (2012–2016). This was true overall and among those with the greatest number of STIs [age 18–34, men who have sex with men (MSM)]. This likely reflects gains in population-wide virologic control through improved antiretroviral therapy and access to care, which helps mitigate the risk of HIV transmission.
AB - Using the incidence of bacterial sexually transmitted infection (STI) as a surrogate for condomless sexual behavior, we assessed the association between STI and uncontrolled HIV replication among in-care persons with HIV (PWH) enrolled in a longitudinal HIV cohort study in the District of Columbia (the DC Cohort). Although STI occurrence initially correlated with higher HIV viral load (VL), this difference became more attenuated over time (2012–2016). This was true overall and among those with the greatest number of STIs [age 18–34, men who have sex with men (MSM)]. This likely reflects gains in population-wide virologic control through improved antiretroviral therapy and access to care, which helps mitigate the risk of HIV transmission.
KW - Ending the HIV Epidemic
KW - HIV
KW - HIV transmission
KW - Sexually transmitted infection
KW - Viral load
UR - https://www.scopus.com/pages/publications/85136490718
U2 - 10.1007/s10461-022-03802-6
DO - 10.1007/s10461-022-03802-6
M3 - Article
C2 - 35984609
AN - SCOPUS:85136490718
SN - 1090-7165
VL - 27
SP - 673
EP - 677
JO - AIDS and Behavior
JF - AIDS and Behavior
IS - 2
ER -