TY - JOUR
T1 - In-Hospital Risk Factors for Reintervention and Amputation in Femoral Arterial Trauma
AU - AAST PROOVIT Study Group
AU - Robbins, Justin M.
AU - Koloditch, Isaac
AU - Walk, Casey
AU - Gramajo, Limayre
AU - Crayton, Corinna
AU - Ekeh, Peter
AU - Wong, Yee
AU - Layba, Cathline
AU - Lenart, Emily
AU - Fischer, Peter E.
AU - Barbee, Kimberly
AU - Morrison, Jonny
AU - Feliciano, David
AU - Scalea, Thomas M.
AU - Skarupa, David
AU - Mull, Jennifer A.
AU - Diaz Zuniga, Yohan
AU - Podbielski, Jeanette M.
AU - Jost, Garrett
AU - Catalano, Richard D.
AU - Penaloza, Liz
AU - Abou-Zamzam, Ahmed M.
AU - Luo-Owen, Xian
AU - Kim, Jennie
AU - Inaba, Kenji
AU - Poulin, Nathaniel
AU - Myers, John
AU - Johnson, Michael
AU - Rocchi, Kristin
AU - Layba, Cathline
AU - Shugar, Samantha
AU - Gilani, Ramyar
AU - Smith, Tikesha
AU - Knight, Reginva
AU - Hammer, Peter
AU - Trexler, Scott T.
AU - Namias, Nicholas
AU - Meizoso, Jonathan P.
AU - Asensio, Juan
AU - Galante, Joseph M.
AU - Humphries, Misty
AU - Rajani, Ravi R.
AU - Benarroch-Gampel, Jaime
AU - Ramos, Christopher
AU - Dulabon, George
AU - Karmy-Jones, Riyad
AU - Larentzakis, Andreas
AU - Velmahos, George
AU - Agarwal, Suresh
AU - Badiee, Jayraan
N1 - Publisher Copyright:
© 2025
PY - 2025/7
Y1 - 2025/7
N2 - Introduction: Known risk factors for surgical reintervention of traumatic femoral artery injuries include thrombosis of vascular reconstruction, kinking of anastomosis, and iatrogenic injury. The literature regarding possible in-hospital risk factors is sparse. We sought to identify risk factors associated with increased reintervention and amputation in this civilian population. Methods: The AAST PROspective Observational Vascular Injury Trial registry was queried for all patients who underwent traumatic femoral arterial repair from 2013 to 2022. Patients with documented need for reintervention and amputation were compared to those without. Results: Three hundred and seventy-six patients required femoral artery repair, 33 (8.8%) needed reintervention, and 21 (5.6%) needed amputation. There was a significant increase in amputation with very high energy injuries and vessel ligation. Intraoperative heparin trended toward significance in protecting against need for reoperation and had a significant decrease in amputations. Postoperative anticoagulation, shunting, and injury repair type showed no difference. Conclusions: This study shows intraoperative heparin and lower energy impact injuries were associated with a lower incidence of limb loss. Further prospective studies are needed to evaluate the effect on reintervention.
AB - Introduction: Known risk factors for surgical reintervention of traumatic femoral artery injuries include thrombosis of vascular reconstruction, kinking of anastomosis, and iatrogenic injury. The literature regarding possible in-hospital risk factors is sparse. We sought to identify risk factors associated with increased reintervention and amputation in this civilian population. Methods: The AAST PROspective Observational Vascular Injury Trial registry was queried for all patients who underwent traumatic femoral arterial repair from 2013 to 2022. Patients with documented need for reintervention and amputation were compared to those without. Results: Three hundred and seventy-six patients required femoral artery repair, 33 (8.8%) needed reintervention, and 21 (5.6%) needed amputation. There was a significant increase in amputation with very high energy injuries and vessel ligation. Intraoperative heparin trended toward significance in protecting against need for reoperation and had a significant decrease in amputations. Postoperative anticoagulation, shunting, and injury repair type showed no difference. Conclusions: This study shows intraoperative heparin and lower energy impact injuries were associated with a lower incidence of limb loss. Further prospective studies are needed to evaluate the effect on reintervention.
KW - Amputation
KW - Femoral trauma
KW - PROOVIT
KW - Reintervention
KW - Risk factors
UR - http://www.scopus.com/inward/record.url?scp=105006835712&partnerID=8YFLogxK
U2 - 10.1016/j.jss.2025.04.047
DO - 10.1016/j.jss.2025.04.047
M3 - Article
AN - SCOPUS:105006835712
SN - 0022-4804
VL - 311
SP - 280
EP - 286
JO - Journal of Surgical Research
JF - Journal of Surgical Research
ER -