In vitro susceptibilities of seven Leptospira species to traditional and newer antibiotics

Duane R. Hospenthal*, Clinton K. Murray

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Human leptospirosis is generally treated with penicillin or doxycycline. We studied the susceptibilities of 11 serovars (seven species) of Leptospira to 14 antibiotics. With the exception of chloramphenicol, all tested agents were at least as potent as penicillin and doxycycline, with the macrolide and ketolide drugs producing the lowest MICs (and minimal bactericidal concentrations).

Original languageEnglish
Pages (from-to)2646-2648
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume47
Issue number8
DOIs
StatePublished - 1 Aug 2003
Externally publishedYes

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