In vitro susceptibilities of seven Leptospira species to traditional and newer antibiotics

Duane R. Hospenthal; Clinton K. Murray

doi:10.1128/AAC.47.8.2646-2648.2003

In vitro susceptibilities of seven Leptospira species to traditional and newer antibiotics

Duane R. Hospenthal^*, Clinton K. Murray

^*Corresponding author for this work

Medicine

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67 Scopus citations

Abstract

Human leptospirosis is generally treated with penicillin or doxycycline. We studied the susceptibilities of 11 serovars (seven species) of Leptospira to 14 antibiotics. With the exception of chloramphenicol, all tested agents were at least as potent as penicillin and doxycycline, with the macrolide and ketolide drugs producing the lowest MICs (and minimal bactericidal concentrations).

Original language	English
Pages (from-to)	2646-2648
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	47
Issue number	8
DOIs	https://doi.org/10.1128/AAC.47.8.2646-2648.2003
State	Published - 1 Aug 2003

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abstract = "Human leptospirosis is generally treated with penicillin or doxycycline. We studied the susceptibilities of 11 serovars (seven species) of Leptospira to 14 antibiotics. With the exception of chloramphenicol, all tested agents were at least as potent as penicillin and doxycycline, with the macrolide and ketolide drugs producing the lowest MICs (and minimal bactericidal concentrations).",

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In vitro susceptibilities of seven Leptospira species to traditional and newer antibiotics

Abstract

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