In-vivo ultrasound assisted tissue engineered articular condyle

Tarek El-Bialy; Hasan Uludag; Walied Moosa; Saranjeev Lalh; Nadr Jomha; Stephen Badylak

In-vivo ultrasound assisted tissue engineered articular condyle

Tarek El-Bialy^*, Hasan Uludag, Walied Moosa, Saranjeev Lalh, Nadr Jomha, Stephen Badylak

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of (LIPUS) on in-vivo functional integration of autologus tissue engineered mandibular condyle (TEMC) for replacement of exercised temporomandibular articular condyles was evaluated. The bone marrow stem cells (BMSC) of rabbits, isolated from their femur bones, were differentiated into chondrogenic or osteogenic cells. The cells were seeded into collagen sponges housed into biodegradable extra-cellular matrix (ECM) scaffold to from TEMCs. The urinary bladder matrix extra-cellular matrix (UBM ECM) was then lyophilized and its six sheets were laminated by vacuum pressing. The left temporomandibular joint (TMJ) in each rabbit was exercised under general anesthesia and Xylazine at a rate of 1 mL/kg. The results show a comparable morphological and dimensional features of the TEMC and normal condyle.

Original language	English
Pages (from-to)	42-43
Number of pages	2
Journal	Canadian Acoustics - Acoustique Canadienne
Volume	36
Issue number	3
State	Published - Sep 2008
Externally published	Yes

Cite this

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title = "In-vivo ultrasound assisted tissue engineered articular condyle",

abstract = "The effects of (LIPUS) on in-vivo functional integration of autologus tissue engineered mandibular condyle (TEMC) for replacement of exercised temporomandibular articular condyles was evaluated. The bone marrow stem cells (BMSC) of rabbits, isolated from their femur bones, were differentiated into chondrogenic or osteogenic cells. The cells were seeded into collagen sponges housed into biodegradable extra-cellular matrix (ECM) scaffold to from TEMCs. The urinary bladder matrix extra-cellular matrix (UBM ECM) was then lyophilized and its six sheets were laminated by vacuum pressing. The left temporomandibular joint (TMJ) in each rabbit was exercised under general anesthesia and Xylazine at a rate of 1 mL/kg. The results show a comparable morphological and dimensional features of the TEMC and normal condyle.",

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T1 - In-vivo ultrasound assisted tissue engineered articular condyle

AU - El-Bialy, Tarek

AU - Uludag, Hasan

AU - Moosa, Walied

AU - Lalh, Saranjeev

AU - Jomha, Nadr

AU - Badylak, Stephen

PY - 2008/9

Y1 - 2008/9

N2 - The effects of (LIPUS) on in-vivo functional integration of autologus tissue engineered mandibular condyle (TEMC) for replacement of exercised temporomandibular articular condyles was evaluated. The bone marrow stem cells (BMSC) of rabbits, isolated from their femur bones, were differentiated into chondrogenic or osteogenic cells. The cells were seeded into collagen sponges housed into biodegradable extra-cellular matrix (ECM) scaffold to from TEMCs. The urinary bladder matrix extra-cellular matrix (UBM ECM) was then lyophilized and its six sheets were laminated by vacuum pressing. The left temporomandibular joint (TMJ) in each rabbit was exercised under general anesthesia and Xylazine at a rate of 1 mL/kg. The results show a comparable morphological and dimensional features of the TEMC and normal condyle.

AB - The effects of (LIPUS) on in-vivo functional integration of autologus tissue engineered mandibular condyle (TEMC) for replacement of exercised temporomandibular articular condyles was evaluated. The bone marrow stem cells (BMSC) of rabbits, isolated from their femur bones, were differentiated into chondrogenic or osteogenic cells. The cells were seeded into collagen sponges housed into biodegradable extra-cellular matrix (ECM) scaffold to from TEMCs. The urinary bladder matrix extra-cellular matrix (UBM ECM) was then lyophilized and its six sheets were laminated by vacuum pressing. The left temporomandibular joint (TMJ) in each rabbit was exercised under general anesthesia and Xylazine at a rate of 1 mL/kg. The results show a comparable morphological and dimensional features of the TEMC and normal condyle.

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JO - Canadian Acoustics - Acoustique Canadienne

JF - Canadian Acoustics - Acoustique Canadienne

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In-vivo ultrasound assisted tissue engineered articular condyle

Abstract

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