Incriminating the inotrope: Dobutamine, eosinophilia, and myocarditis

Abigail M. Chang; Rachel U. Lee; Lillian E. Grobman; Omonigho A. Aisagbonhi; Bruce L. Zuraw; Sandra C. Christiansen

doi:10.1016/j.jacig.2026.100680

Incriminating the inotrope: Dobutamine, eosinophilia, and myocarditis

Abigail M. Chang
, Rachel U. Lee
, Lillian E. Grobman
, Omonigho A. Aisagbonhi
, Bruce L. Zuraw^*
, Sandra C. Christiansen

^*Corresponding author for this work

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

This report of dobutamine-associated eosinophilia, fever, and eosinophilic myocardial hypersensitivity illustrates the substantial risk of severe sequelae stemming from diagnostic delay. Recognition of this rare condition should catalyze exploration for feasible dobutamine alternatives, thereby minimizing morbidity and optimizing outcomes.

Original language	English
Article number	100680
Journal	Journal of Allergy and Clinical Immunology: Global
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.jacig.2026.100680
State	Published - May 2026

Keywords

EMH
Eosinophilia
dobutamine
hypersensitivity
myocarditis

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10.1016/j.jacig.2026.100680

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title = "Incriminating the inotrope: Dobutamine, eosinophilia, and myocarditis",

abstract = "This report of dobutamine-associated eosinophilia, fever, and eosinophilic myocardial hypersensitivity illustrates the substantial risk of severe sequelae stemming from diagnostic delay. Recognition of this rare condition should catalyze exploration for feasible dobutamine alternatives, thereby minimizing morbidity and optimizing outcomes.",

keywords = "EMH, Eosinophilia, dobutamine, hypersensitivity, myocarditis",

author = "Chang, \{Abigail M.\} and Lee, \{Rachel U.\} and Grobman, \{Lillian E.\} and Aisagbonhi, \{Omonigho A.\} and Zuraw, \{Bruce L.\} and Christiansen, \{Sandra C.\}",

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AU - Chang, Abigail M.

AU - Lee, Rachel U.

AU - Grobman, Lillian E.

AU - Aisagbonhi, Omonigho A.

AU - Zuraw, Bruce L.

AU - Christiansen, Sandra C.

PY - 2026/5

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AB - This report of dobutamine-associated eosinophilia, fever, and eosinophilic myocardial hypersensitivity illustrates the substantial risk of severe sequelae stemming from diagnostic delay. Recognition of this rare condition should catalyze exploration for feasible dobutamine alternatives, thereby minimizing morbidity and optimizing outcomes.

KW - EMH

KW - Eosinophilia

KW - dobutamine

KW - hypersensitivity

KW - myocarditis

UR - https://www.scopus.com/pages/publications/105034116361

U2 - 10.1016/j.jacig.2026.100680

DO - 10.1016/j.jacig.2026.100680

M3 - Article

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VL - 5

JO - Journal of Allergy and Clinical Immunology: Global

JF - Journal of Allergy and Clinical Immunology: Global

IS - 3

M1 - 100680

ER -

Incriminating the inotrope: Dobutamine, eosinophilia, and myocarditis

Abstract

Keywords

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