Infections due to non-candidal yeasts

Invasive fungal infections have become an important cause of morbidity and mortality over the past two decades. More recently, uncommon fungi have been increasingly reported. The increased frequency may be due to an improved identification and reporting system, or an increase in the number of severely immunocompromised hosts. Diagnosing infections due to these rare or uncommon yeast are a challenge, since the majority of the time we rely on traditional microbiologic assays and not improved diagnostic assays. Evolving taxonomy has further contributed to the complexity of recognizing an isolate's significance. In addition, the management of these types of fungal infections is difficult because of the lack of data, specifically, the lack of adequate in vitro susceptibility studies, and the paucity of any clinical treatment trials.